M. Concari
University of Modena and Reggio Emilia
16 Papers
217 Citations
M. Concari is an academic researcher from University of Modena and Reggio Emilia. The author has contributed to research in topics: Bile acid & Cholesterol. The author has an hindex of 9, co-authored 16 publications.
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Papers
Effect of aging on cholesterol 7 alpha-hydroxylation in humans.
Marco Bertolotti,Nicola Abate,S. Bertolotti,Paola Loria,M. Concari,R. Messora,Francesca Carubbi,Adriano Pinetti,Nicola Carulli +8 more
TL;DR: The data are consistent with a reduced rate of conversion of cholesterol to bile acids with aging, particularly in females, and suggest a coordinate reduction of triglyceride production.
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Effects of Different Phenotypes of Hyperlipoproteinemia and of Treatment With Fibric Acid Derivatives on the Rates of Cholesterol 7α-Hydroxylation in Humans
Marco Bertolotti,M. Concari,Paola Loria,Nicola Abate,Adriano Pinetti,M. Eugenia Guicciardi,Nicola Carulli +6 more
TL;DR: The effects of different hyperlipoproteinemic conditions and of treatment with fibric acid derivatives on the rates of cholesterol 7 alpha-hydroxylation (the limiting step of bile acid synthesis) in humans are investigated.
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Review article: effect of bile salt pool composition on hepatic and biliary functions.
N. Carulli,Marco Bertolotti,Francesca Carubbi,M. Concari,P. Martella,Lucia Carulli,Paola Loria +6 more
TL;DR: It is concluded that the regulatory effects of bile acids on the liver and biliary tract are largely dependent on the hydrophobic–hydrophilic balance of the recirculating bile acid pool.
Growth of human herpesvirus 6 in HepG2 cells
Claudio Cermelli,M. Concari,Francesca Carubbi,Giuliana Fabio,Anna Sabbatini,Monica Pecorari,Paola Pietrosemoli,Marisa Meacci,E. Guicciardi,Nicola Carulli,Marinella Portolani +10 more
TL;DR: HepG2 cells, a well differentiated liver cell line, were shown to be permissive for both human herpesvirus 6 (HHV-6) A and B strains by three independent methods of analysis: detection of viral antigens, viral DNA sequences and infectious virus.
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Suppression of bile acid synthesis, but not of hepatic cholesterol 7α-hydroxylase expression, by obstructive cholestasis in humans
Marco Bertolotti,Lucia Carulli,M. Concari,P. Martella,Paola Loria,Enrico Tagliafico,Sergio Ferrari,Marina Del Puppo,Barbara Amati,Emma De Fabiani,Maurizio Crestani,Claudio Amorotti,Antonio Manenti,Francesca Carubbi,Adriano Pinetti,Nicola Carulli +15 more
TL;DR: Suppression of in vivo bile acid synthesis with no corresponding reduction in tissue 7α‐hydroxylase expression and activity is consistent with nontranscriptional, posttranslational levels of regulation; these may play a role in the feedback control of bile Acid synthesis in particular conditions.
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