Lyvia Fourcade
Université de Montréal
5 Papers
42 Citations
Lyvia Fourcade is an academic researcher from Université de Montréal. The author has contributed to research in topics: Population & Gene. The author has an hindex of 4, co-authored 4 publications.
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Papers
Blood B Lymphocyte Stimulator (BLyS)/BAFF levels may reflect natural immunity to HIV in highly exposed uninfected Beninese Commercial Sex Workers.
Catherine Sabourin-Poirier,Lyvia Fourcade,Josiane Chagnon-Choquet,Annie-Claude Labbé,Michel Alary,Fernand Guédou,Johanne Poudrier,Michel Roger +7 more
TL;DR: Blood BLyS levels and B-cell status in HIV highly-exposed commercial sex workers (CSWs) from Benin were found to be lower than those observed in both HIV-infected CSW and HIV-uninfected non-CSW groups.
Highly-Exposed HIV-1 seronegative Female Commercial Sex Workers sustain in their genital mucosa increased frequencies of tolerogenic myeloid and regulatory T-cells.
Valérie Thibodeau,Lyvia Fourcade,Annie-Claude Labbé,Michel Alary,Fernand Guédou,Johanne Poudrier,Michel Roger +6 more
TL;DR: Characters of TLR-7, IFN-α, IL-10, HLA-G and ILT-4 expression profiles in the genital tract of female CSWs and HIV-1-uninfected non-CSWs from Benin provide strong evidence to support the implication of tolerogenic myeloid cells expressing high levels of antiviral molecules in shaping the genital mucosal immune response to prevent HIV infection.
Natural Immunity to HIV: A Template for Vaccine Strategies
TL;DR: HESN individuals provide an exceptional opportunity to identify important clues for the development of protective devices, and efforts should aim at soliciting immune responses observed in the context of their natural immunity to HIV.
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Monocyte Gene and Molecular Expression Profiles Suggest Distinct Effector and Regulatory Functions in Beninese HIV Highly Exposed Seronegative Female Commercial Sex Workers
Laurence Blondin-Ladrie,Lyvia Fourcade,Alessandro Modica,Matheus Aranguren,Nicolas de Montigny,Annie-Claude Labbé,Michel Alary,Fernand Guédou,Johanne Poudrier,Michel Roger +9 more
TL;DR: The blood monocyte compartment of Beninese HESNs is characterized and shows increased expression levels of effector CD16, CD11c,CD11b, as well as regulatory HLA-G, IL-10, and IFN-α markers when compared to HIV-uninfected women and/or HIV-infected CSWs, which likely confers an enormous advantage in their resistance to HIV infection.
Natural Immunity to HIV is associated with Low BLyS/BAFF levels and low frequencies of innate marginal zone like CD1c+ B-cells in the genital tract.
Lyvia Fourcade,Catherine Sabourin-Poirier,Victoire Perraud,Marie-Claude Faucher,Josiane Chagnon-Choquet,Annie-Claude Labbé,Annie-Claude Labbé,Michel Alary,Fernand Guédou,Johanne Poudrier,Michel Roger +10 more
TL;DR: It is shown that HIV highly-exposed seronegative (HESN) commercial sex workers (CSWs) had lower soluble BLyS/BAFF levels and relative frequencies of BLYS/ BAFF expressing cells in their genital mucosa when compared to those from HIV-infected CSWs and HIV-uninfected non-CSWs.