Lydia Mare
University of Insubria
9 Papers
85 Citations
Lydia Mare is an academic researcher from University of Insubria. The author has contributed to research in topics: Antigen & Chromosome 20. The author has an hindex of 6, co-authored 9 publications.
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Papers
Suppression of β1,3galactosyltransferase β3Gal‐T5 in cancer cells reduces sialyl‐Lewis a and enhances poly N‐acetyllactosamines and sialyl‐Lewis x on O‐glycans
Lydia Mare,Marco Trinchera +1 more
TL;DR: It is suggested that beta 3Gal-T5 plays a relevant role in gastrointestinal and pancreatic tissues counteracting the glycosylation pattern associated to malignancy, and is necessary for the synthesis and secretion of CA19.9 antigen, whose expression still depends on multiple interacting factors.
32
CA19.9 antigen circulating in the serum of colon cancer patients: where is it from?
TL;DR: The tetrasaccharide epitope sialyl-Lewis a studying the biosynthesis, expression, and secretion in colon cancers and related cancer cell lines is found to be dramatically reduced in colon adenocarcinomas, in terms of both transcript and enzyme activity levels.
24
Comparative Analysis of Retroviral and Native Promoters Driving Expression of β1,3-Galactosyltransferase β3Gal-T5 in Human and Mouse Tissues
Lydia Mare,Marco Trinchera +1 more
TL;DR: The CCAAT-binding factor binding site and the entire downstream sequence driving the expression of type A transcripts in humans are structurally and functionally conserved in mice, where they constitute a uniqueβ3Gal-T5 promoter that appears to be the ancestral promoter of the gene.
23
Cytogenetic monitoring in Shwachman-Diamond syndrome: a note on clonal progression and a practical warning.
Barbara Pressato,Roberto Valli,Cristina Marletta,Lydia Mare,Giuseppe Montalbano,Francesco Lo Curto,Francesco Pasquali,Emanuela Maserati +7 more
TL;DR: The lack of any clonal progression and the frequent appearance of independent clones with chromosomal changes different from the one initially discovered, with possible severe prognostic implications, are reported.
20
Clonal chromosome anomalies affecting FLI1 mimic inherited thrombocytopenia of the Paris‐Trousseau type
Patrizia Noris,Roberto Valli,Alessandro Pecci,Cristina Marletta,Rosangela Invernizzi,Lydia Mare,Carlo L. Balduini,Emanuela Maserati +7 more
TL;DR: The thrombocytopenia of the Paris‐Trousseau (TCPT) type is a contiguous gene syndrome characterized by mild bleeding tendency, variable thromBocy Topenia (THC), abnormal giant alpha‐granules in platelets and dysmegakaryopoiesis.