Lukas Havla
Ludwig Maximilian University of Munich
13 Papers
49 Citations
Lukas Havla is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Perfusion scanning & Medicine. The author has an hindex of 6, co-authored 13 publications.
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Papers
Regorafenib effects on human colon carcinoma xenografts monitored by dynamic contrast-enhanced computed tomography with immunohistochemical validation.
Clemens C. Cyran,Philipp M. Kazmierczak,Heidrun Hirner,Matthias Moser,Michael Ingrisch,Lukas Havla,Alexandra Michels,Ralf S. Eschbach,B. Schwarz,Maximilian F. Reiser,Christiane Bruns,Konstantin Nikolaou +11 more
TL;DR: Regorafenib significantly suppressed tumor vascularity (plasma volume) quantified by dynamic contrast-enhanced computed tomography in experimental colon carcinomas in rats with good-to-moderate correlations to an immunohistochemical gold standard.
Detection of single-phase CTA occult vessel occlusions in acute ischemic stroke using CT perfusion-based wavelet-transformed angiography.
Wolfgang G. Kunz,Wieland H. Sommer,Lukas Havla,Franziska Dorn,Felix G. Meinel,Olaf Dietrich,Grete Buchholz,Birgit Ertl-Wagner,Kolja M. Thierfelder +8 more
TL;DR: waveletCTA is able to detect spCTA occult vessel occlusions in about half of acute ischemic stroke patients and may potentially identify more patients eligible for endovascular therapy.
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Monitoring Cell Death in Regorafenib-Treated Experimental Colon Carcinomas Using Annexin-Based Optical Fluorescence Imaging Validated by Perfusion MRI.
Philipp M. Kazmierczak,Egon Burian,Ralf S. Eschbach,Heidrun Hirner-Eppeneder,Matthias Moser,Lukas Havla,Michel Eisenblätter,Maximilian F. Reiser,Konstantin Nikolaou,Clemens C. Cyran +9 more
TL;DR: Annexin-based OI allowed for the non-invasive monitoring of regorafenib-induced early cell death in experimental colon carcinomas in rats, validated by perfusion MRI and multiparametric immunohistochemistry.
DCE-MRI biomarkers for monitoring an anti-angiogenic triple combination therapy in experimental hypopharynx carcinoma xenografts with immunohistochemical validation
A. Sterzik,Philipp M. Paprottka,Pamela Zengel,Heidrun Hirner,Svenja Roßpunt,Ralf S. Eschbach,Matthias Moser,Lukas Havla,Michael Ingrisch,Brigitte Mack,Maximilian F. Reiser,Konstantin Nikolaou,Clemens C. Cyran +12 more
TL;DR: DCE-MRI may be a suitable tool for the non-invasive monitoring of the anti-vascular effects of this innovative triple therapy regimen with potential for clinical translation.
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Wavelet-based calculation of cerebral angiographic data from time-resolved CT perfusion acquisitions.
TL;DR: The proposed calculation approach for angiography data using temporal wavelet transforms of intracranial CT perfusion datasets provides higher vascular contrast and intrinsic removal of non-enhancing structures such as bone.
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