Lukas E. Brümmer
Heidelberg University
5 Papers
Lukas E. Brümmer is an academic researcher from Heidelberg University. The author has contributed to research in topics: Medicine & Meta-regression. The author has an hindex of 1, co-authored 1 publications.
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Papers
Accuracy of rapid point-of-care antigen-based diagnostics for SARS-CoV-2: An updated systematic review and meta-analysis with meta-regression analyzing influencing factors
Lukas E. Brümmer,Stephan Katzenschlager,Sean McGrath,Stephan Schmitz,Mary Gaeddert,C. Erdmann,Marc Bota,Maurizio Grilli,Jan Larmann,Markus A. Weigand,Nira R. Pollock,Aurélien Macé,Berra Erkosar,S. Carmona,Jilian A. Sacks,Stefano Ongarello,Claudia M. Denkinger +16 more
TL;DR: Ag-RDTs detect most of the individuals infected with SARS-CoV-2, and almost all when high viral loads are present, they are especially useful to detect persons with high viral load who are most likely to transmit the virus.
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Comparing SARS-CoV-2 antigen-detection rapid diagnostic tests for COVID-19 self-testing/self-sampling with molecular and professional-use tests: a systematic review and meta-analysis
Stephan Katzenschlager,Lukas E. Brümmer,Stephani Schmitz,Hannah Tolle,Katharina Manten,Mary Gaeddert,C. Erdmann,Andreas Lindner,Frank Tobian,Maurizio Grilli,Nira R. Pollock,Aurélien Macé,Berra Erkosar,Sergio Carmona,Stefano Ongarello,Cheryl C. Johnson,Jilian A. Sacks,Claudia M. Denkinger,Seda Yerlikaya +18 more
TL;DR: Despite high heterogeneity among studies, COVID-19 self-testing/self-sampling exhibits high concordance with professional-use Ag-RDTs, which suggests that self- Testing and self-Sampling can be offered as part of CO VID-19 testing strategies.
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Accuracy of package inserts of SARS-CoV-2 rapid antigen tests: a secondary analysis of manufacturer versus systematic review data.
Jacob Bigio,Emily L-H MacLean,Rishav Das,Giorgia Sulis,Mikashmi Kohli,Sarah Berhane,Jacqueline Dinnes,Jonathan J. Deeks,Lukas E. Brümmer,Claudia M. Denkinger,Madhukar Pai +10 more
TL;DR: Health professionals and the public should be aware that package inserts for SARS-CoV-2 RATs might provide an overly optimistic picture of the sensitivity of a test.
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The accuracy of novel antigen rapid diagnostics for SARS-CoV-2: a living systematic review and meta-analysis.
Lukas E. Brümmer,Stephan Katzenschlager,Mary Gaeddert,Christian Erdmann,Stephani Schmitz,Marc Bota,Maurizio Grilli,Jan Larmann,Markus A. Weigand,Nira R. Pollock,Sergio Carmona,Stefano Ongarello,Jilian A. Sacks,Claudia M. Denkinger +13 more
TL;DR: In this article, a systematic review and meta-analysis of commercially available rapid diagnostic tests (Ag-RDTs) is presented, where the clinical accuracy (sensitivity and specificity) of these tests are assessed.
Cost effectiveness of low-complexity screening tests in community-based case-finding for tuberculosis.
Lukas E. Brümmer,Ryan R Thompson,Akash Malhotra,Sourya Shrestha,Emily A. Kendall,Jason R. Andrews,Patrick P. J. Phillips,Payam Nahid,Adithya Cattamanchi,Florian M. Marx,Claudia M. Denkinger,David W. Dowdy +11 more
TL;DR: Screening tests can meaningfully improve the cost-effectiveness of community-based case-finding for TB but only if they are sensitive, specific, and inexpensive.