Luiz Belardinelli
University of Florida
430 Papers
5.8K Citations
Luiz Belardinelli is an academic researcher from University of Florida. The author has contributed to research in topics: Adenosine & Ranolazine. The author has an hindex of 81, co-authored 422 publications. Previous affiliations of Luiz Belardinelli include Cornell University & University of Florida Health.
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Papers
Antitorsadogenic Effects of (±)- N -(2,6-Dimethyl-phenyl)-(4[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazine (Ranolazine) in Anesthetized Rabbits
TL;DR: It is concluded that ranolazine antagonizes the ventricular repolarization changes caused by clofilium and suppresses cl ofilium-induced TdP in rabbits.
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•Journal Article
Antagonism of the effects of adenosine and hypoxia on atrioventricular conduction time by two novel alkylxanthines: correlation with binding to adenosine A1 receptors.
TL;DR: BW A533U and BW A1433U were shown to attenuate hypoxia-induced AH interval prolongation and compete for binding of 125I-aminobenzyladenosine to ventricular membranes and inhibit myocardial phosphodiesterase.
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Binding of the Novel Nonxanthine A2A Adenosine Receptor Antagonist [3H]SCH58261 to Coronary Artery Membranes
Luiz Belardinelli,John C. Shryock,Jackie Ruble,Angela Monopoli,Silvio Dionisotti,Ennio Ongini,Donn M. Dennis,Stephen P. Baker +7 more
TL;DR: The different rank orders of potencies for agonists and antagonists at A2A receptors of porcine coronary arteries, striatum, and PC12 cells and significant differences in absolute values of potency of ligands in the three preparations may indicate the existence of different subtypes of A 2AAdoRs.
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Effects of dipyridamole and aminophylline on hemodynamics, regional myocardial blood flow and thallium-201 washout in the setting of a critical coronary stenosis
TL;DR: In a canine model of partial coronary stenosis, systemic hypotension, adverse regional flow effects (coronary steal) and prolonged thallium-201 washout consequent to intravenously administered dipyridamole are promptly reversed by intravenous aminophylline administration.
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Atrioventricular nodal accommodation in isolated guinea pig hearts: physiological significance and role of adenosine.
J R Jenkins,Luiz Belardinelli +1 more
TL;DR: Dipyridamole (1 microM), an adenosine uptake blocker, markedly accentuates the AVN conduction time prolongation, accentuated the AV block associated with fast atrial rates, and significantly increased the Wenckebach cycle length.
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