Luise Florin
University of Mainz
47 Papers
142 Citations
Luise Florin is an academic researcher from University of Mainz. The author has contributed to research in topics: Tetraspanin & Endosome. The author has an hindex of 24, co-authored 44 publications.
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Papers
Reorganization of Nuclear Domain 10 Induced by Papillomavirus Capsid Protein L2
TL;DR: It is shown that the minor capsid protein L2 of human papillomavirus (HPV) type 33 induces a reorganization of ND10-associated proteins, and the differential change in protein composition observed provides further evidence to suggest that the ND10 -associated proteins are an important interface of viral life cycle and host cell.
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Impact of VP1-Specific Protein Sequence Motifs on Adeno-Associated Virus Type 2 Intracellular Trafficking and Nuclear Entry
Ruth Popa-Wagner,Manvi Porwal,Michael Kann,Matthias Reuss,Marc Weimer,Luise Florin,Jürgen A. Kleinschmidt +6 more
TL;DR: Interestingly, intracellular trafficking of AAV2 was shown to be independent of PLA2 activity, and mutation of three PDZ-binding motifs revealed a nuclear transport-defective phenotype, suggesting a role in nuclear uptake of the virus through an as-yet-unknown mechanism.
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Tannins from Hamamelis virginiana bark extract: characterization and improvement of the antiviral efficacy against influenza A virus and human papillomavirus.
Linda L. Theisen,Clemens A. J. Erdelmeier,Gilles A. Spoden,Fatima Boukhallouk,Aurélie Sausy,Luise Florin,Claude P. Muller +6 more
TL;DR: This work demonstrates antiviral activity of the bark extract against different IAV strains, including the recently emerged H7N9, and shows for the first time that a tannin-rich extract inhibits human papillomavirus (HPV) type 16 infection.
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Polyethylenimine Is a Strong Inhibitor of Human Papillomavirus and Cytomegalovirus Infection
Gilles A. Spoden,Katrin Besold,Steffi Krauter,Bodo Plachter,Nils Hanik,Andreas F. M. Kilbinger,Carsten Lambert,Luise Florin +7 more
TL;DR: Polyethylenimine concentrations required for inhibition of human papillomavirus and cytomegalovirus did not cause any cytotoxic effects and may thus be attractive molecules for the development of antiviral microbicides.
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Human Papillomavirus Types 16, 18, and 31 Share Similar Endocytic Requirements for Entry
Gilles A. Spoden,Lena Kühling,Nicole Cordes,Bettina Frenzel,Martin Sapp,Klaus Boller,Luise Florin,Mario Schelhaas +7 more
TL;DR: HPV18 (like HPV16 and -31) entry was independent of clathrin, caveolin, dynamin, and lipid rafts but required actin polymerization and tetraspanin CD151, and the viruses were routed to the same LAMP-1-positive compartment, so the viruses shared similar cellular requirements for endocytic entry.
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