Luisa Caione
University of Turin
10 Papers
51 Citations
Luisa Caione is an academic researcher from University of Turin. The author has contributed to research in topics: Haematopoiesis & Purinergic signalling. The author has an hindex of 7, co-authored 10 publications.
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Papers
Tumor angiogenesis and progression are enhanced by Sema4D produced by tumor-associated macrophages.
Jose Rafael Sierra,Simona Corso,Luisa Caione,Virna Cepero,Paolo Conrotto,Alessandro Cignetti,Wanda Piacibello,Atsushi Kumanogoh,Hitoshi Kikutani,Paolo M. Comoglio,Luca Tamagnone,Silvia Giordano +11 more
TL;DR: It is demonstrated that tumor-associated macrophages (TAMs) are the main cells producing Sema 4D within the tumor stroma and that their ability to produce Sema4D is critical for tumor angiogenesis and vessel maturation.
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Enhanced c-Met activity promotes G-CSF–induced mobilization of hematopoietic progenitor cells via ROS signaling
Melania Tesio,Melania Tesio,Karin Golan,Simona Corso,Silvia Giordano,Amir Schajnovitz,Yaron Vagima,Shoham Shivtiel,Alexander Kalinkovich,Luisa Caione,Loretta Gammaitoni,Elisa Laurenti,Eike C. Buss,Eike C. Buss,Elias Shezen,Tomer Itkin,Orit Kollet,Isabelle Petit,Andreas Trumpp,Andreas Trumpp,James G. Christensen,Massimo Aglietta,Wanda Piacibello,Tsvee Lapidot +23 more
TL;DR: The data show dynamic c-Met expression and function in the bone marrow and show that enhanced c- Met signaling is crucial to facilitate stress-induced mobilization of progenitor cells as part of host defense and repair mechanisms.
136
Inhibition of erythropoiesis in malaria anemia: role of hemozoin and hemozoin-generated 4-hydroxynonenal
Oleksii A. Skorokhod,Luisa Caione,Tiziana Marrocco,Giorgia Migliardi,Valentina Barrera,Paolo Arese,Wanda Piacibello,Evelin Schwarzer +7 more
TL;DR: Present data confirm the inhibitory role of HZ, identify HNE as one HZ-generated inhibitory molecule and describe molecular targets of HNE in erythroid progenitors possibly involved in ERYthropoiesis inhibition in malaria anemia.
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Purinergic stimulation of human mesenchymal stem cells potentiates their chemotactic response to CXCL12 and increases the homing capacity and production of proinflammatory cytokines.
Davide Ferrari,Sara Gulinelli,Valentina Salvestrini,Giovanna Lucchetti,Roberta Zini,Rossella Manfredini,Luisa Caione,Wanda Piacibello,Marilena Ciciarello,Lara Rossi,Marco Idzko,Sergio Ferrari,Francesco Di Virgilio,Roberto M. Lemoli +13 more
TL;DR: The data show that purinergic signaling modulates hMSCs functions and highlights a role for extracellular nucleotides in h MSCs biology.
80
Fast but durable megakaryocyte repopulation and platelet production in NOD/SCID mice transplanted with ex-vivo expanded human cord blood CD34+ cells.
Stefania Bruno,Monica Gunetti,Loretta Gammaitoni,Eliana Perissinotto,Luisa Caione,Fiorella Sanavio,Franca Fagioli,Massimo Aglietta,Wanda Piacibello +8 more
TL;DR: A stroma‐free culture is established that allows the maintenance and the expansion for several weeks of a cord blood (CB) CD34+ cell population capable of multilineage and long‐lasting hematopoietic repopulation in non‐obese diabetic/ severe combined immunodeficient (NOD/SCID) mice.