Luisa Bell
University of Würzburg
5 Papers
4 Citations
Luisa Bell is an academic researcher from University of Würzburg. The author has contributed to research in topics: CD3 & Multiple sclerosis. The author has an hindex of 3, co-authored 5 publications.
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Papers
Lymphoid Aggregates in the CNS of Progressive Multiple Sclerosis Patients Lack Regulatory T Cells.
Luisa Bell,Alexander Lenhart,Andreas Rosenwald,Camelia M. Monoranu,Friederike Berberich-Siebelt +4 more
TL;DR: E ectopic lymphoid follicles (eLFs) were identified at the inflamed meninges of patients with progressive multiple sclerosis, pointing to less controlled humoral immune responses in those lymphoid aggregates possibly enabling the occurrence of CNS-specific autoantibodies in multiple sclerosis patients.
The mere physical presence of another person reduces human autonomic responses to aversive sounds.
TL;DR: The results indicate that the mere presence of another person was sufficient to diminish autonomic responses to aversive events in humans, and thus verify the translational validity of basic social modulation effects across different species.
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Rapid and Efficient Gene Editing for Direct Transplantation of Naive Murine Cas9+ T Cells.
Snigdha Majumder,Isabelle Jugovic,Domenica Saul,Luisa Bell,Nadine Hundhausen,Rishav Seal,Andreas Beilhack,Andreas Rosenwald,Dimitrios Mougiakakos,Friederike Berberich-Siebelt +9 more
TL;DR: In this paper, the authors demonstrate nucleofection of pre-stimulated and naive CD3+ T cells with guideRNA only, and demonstrate the necessity of gene-editing and transferring unstimulated human T cells during allogenic hematopoietic stem cell transplantation.
Bone marrow-derived myeloid progenitors in the leptomeninges of adult mice
Tobias Koeniger,Luisa Bell,Anika Mifka,Michael Enders,Valentin Hautmann,Subba Rao Mekala,Philipp Kirchner,Arif B. Ekici,Christian Schulz,Philipp Wörsdörfer,Stine Mencl,Christoph Kleinschnitz,Süleyman Ergün,Stefanie Kuerten,Stefanie Kuerten,Stefanie Kuerten +15 more
TL;DR: The presence of myeloid progenitors at the meningeal border of the brain is confirmed and the foundation to unravel their possible functions in CNS surveillance and local immune cell production is laid.
4
Characterization of blood-brain barrier integrity in a B-cell-dependent mouse model of multiple sclerosis.
TL;DR: Evaluating BBB integrity in the context of B-cell-dependent neuroinflammation in a mouse model of MS underscores that a leaky BBB is a characteristic feature of EAE, but suggests that extent and region specificity of BBB damage differs between individual EAE models that vary in the underlying immunopathology.