Luis A. Castillo
Academia Nacional de Medicina
10 Papers
1 Citations
Luis A. Castillo is an academic researcher from Academia Nacional de Medicina. The author has contributed to research in topics: Neutrophil extracellular traps & Medicine. The author has an hindex of 3, co-authored 7 publications.
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Papers
Klebsiella pneumoniae ST258 Negatively Regulates the Oxidative Burst in Human Neutrophils.
Luis A. Castillo,Federico Birnberg-Weiss,Nahuel Rodriguez-Rodrigues,Daiana Martire-Greco,Fabiana Bigi,Verónica I Landoni,Sonia A. Gómez,Gabriela C. Fernández +7 more
TL;DR: A mechanism of immune evasion of Kpn KPC ST258 is unraveled, which may contribute to design more effective strategies for the treatment of these multi-resistant bacterial infections.
Prokaryotic RNA Associated to Bacterial Viability Induces Polymorphonuclear Neutrophil Activation.
Nahuel Rodriguez-Rodrigues,Luis A. Castillo,Verónica I Landoni,Daiana Martire-Greco,M. Ayelén Milillo,Paula Barrionuevo,Gabriela C. Fernández +6 more
TL;DR: It is found that bacterial viability was indispensable to induce PMN activation, as measured by forward-scatter increase, CD11b surface expression, chemotaxis, reactive oxygen species (ROS) generation and neutrophil extracellular trap (NET) formation, and this sensing triggers potent bactericidal mechanisms.
Brucella abortus-infected platelets modulate the activation of neutrophils.
Aldana Trotta,M. Ayelén Milillo,Agustina Serafino,Luis A. Castillo,Federico Birnberg Weiss,M. Victoria Delpino,Guillermo H. Giambartolomei,Gabriela C. Fernández,Paula Barrionuevo +8 more
TL;DR: It is demonstrated that PLTs interact with neutrophils and promote a proinflammatory phenotype which could also contribute to the resolution of the infection.
Prokaryotic RNA activates endothelial cells promoting neutrophil transmigration.
Luis A. Castillo,Federico Birnberg Weiss,Nahuel Rodriguez-Rodrigues,Jose R Pittaluga,Daiana Martire-Greco,Maria A Milillo,Sebastian F Grinstein,María R Camelli,Ana J Mena Aybar,Verónica I Landoni,Gabriela C. Fernández +10 more
TL;DR: Results indicate that pRNA activates EC, resulting in the modulation of EC–PMN interaction by inducing PMN chemotaxis, adhesion and activation.
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Humoral response to the BBIBP-CorV vaccine over time in healthcare workers with or without exposure to SARS-CoV-2
Maria Noel Badano,Florencia Sabbione,Irene Angélica Keitelman,Matias Javier Pereson,Natalia Aloisi,Ana Colado,Victoria Ramos,Juan Manuel Ortiz Wilczynski,Roberto Gabriel Pozner,Luis A. Castillo,Georgina Wigdorovitz,Maria M.E. de Bracco,S. Fink,Roberto Chuit,Patricia Baré +14 more
TL;DR: In this paper, SARS-CoV-2-specific humoral response was analyzed over time in a group of healthcare workers who underwent vaccination with BBIBP-CorV (Sinopharm) vaccine in Argentina.