Lufeng Ding

TL;DR: A new microscopy method of Volumetric Imaging with Synchronized on-the-fly-scan and Readout (VISoR) for high-throughput, high-quality brain mapping, combining synchronized scanning beam illumination and oblique imaging over cleared tissue sections in smooth motion, effectively eliminates motion blur to obtain undistorted images.

TL;DR: A new light-sheet microscopy method for fast, large-scale volumetric imaging that achieves high-speed 3D image acquisition of an entire mouse brain within 2 hours, at a resolution capable of resolving synaptic spines is described.

TL;DR: An integrative approach that combines primate-optimized tissue sectioning and clearing with ultrahigh-speed, large-scale, volumetric fluorescence microscopy, capable of completing whole-brain imaging of a rhesus monkey within 100 hours is presented.

TL;DR: In this article, a high-speed three-dimensional microscopic imaging device and method is presented, where an excitation device generates detectable contrast in the to-be-measured area of a sample along the direction of an exciting principal axis; a detection device detects the contrast generated in the detected area of the sample along a detection principal axis, and a moving mechanism generates the movement relative to the sample and the detection device; the moving mechanism moves the sample to an imaging area continuously at a uniform speed, and images are continuously collected while the sample is moving, and thus,