Lufan Li
Nanjing Medical University
13 Papers
8 Citations
Lufan Li is an academic researcher from Nanjing Medical University. The author has contributed to research in topics: Stem cell & Biology. The author has an hindex of 5, co-authored 9 publications.
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Papers
Reprogramming of Meiotic Chromatin Architecture during Spermatogenesis
Yao Wang,Hanben Wang,Yu Zhang,Zhenhai Du,Wei Si,Suixing Fan,Dongdong Qin,Mei Wang,Yanchao Duan,Lufan Li,Yuying Jiao,Yuanyuan Li,Qiujun Wang,Qinghua Shi,Xin Wu,Wei Xie +15 more
TL;DR: Interestingly, it is found that topologically associating domains (TADs) undergo dissolution and reestablishment in spermatogenesis in rhesus monkey using low-input Hi-C, suggesting that the synaptonemal complex may restrict TADs and promote local compartments.
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A long non-coding RNA interacts with Gfra1 and maintains survival of mouse spermatogonial stem cells
TL;DR: The data provide the first evidence that long non-coding RNAs (lncRNAs) regulate SSC fate, and lncRNA033862 knockdown severely impairs SSC survival and their capacity to repopulate recipient testes in a transplantation assay.
The Glial Cell-Derived Neurotrophic Factor (GDNF)-responsive Phosphoprotein Landscape Identifies Raptor Phosphorylation Required for Spermatogonial Progenitor Cell Proliferation
Min Wang,Yueshuai Guo,Mei Wang,Tao Zhou,Yuanyuan Xue,Guihua Du,Xiang Wei,Jing Wang,Lin Qi,Hao Zhang,Lufan Li,Lan Ye,Xuejiang Guo,Xin Wu +13 more
TL;DR: These findings implicate previously undescribed signaling networks in governing fate decision of SPCs, which is essential for the understanding of spermatogenesis and of potential consequences of pathogenic insult for male infertility.
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mRBPome capture identifies the RNA-binding protein TRIM71, an essential regulator of spermatogonial differentiation.
Guihua Du,Guihua Du,Xinrui Wang,Mengcheng Luo,Mengcheng Luo,Weiya Xu,Tao Zhou,Mei Wang,Luping Yu,Lufan Li,Li'e Cai,P. Jeremy Wang,John Zhong Li,Jon M. Oatley,Xin Wu +14 more
TL;DR: Findings demonstrate a key role of the RBP system in regulation of the spermatogenic lineage and may provide clues about the influence of RBPs on the biology of progenitor cell populations in other lineages.
LIN28A binds to meiotic gene transcripts and modulates translation in male germ cells
TL;DR: It is shown that the RNA-binding protein LIN28A enhances the translation of target mRNAs involved in meiosis in male germline cells and male fertility in mammals through HITS-CLIP and RNA-seq.
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