Lucie Heinzerling
University of Zurich
21 Papers
170 Citations
Lucie Heinzerling is an academic researcher from University of Zurich. The author has contributed to research in topics: T cell & Cutaneous T-cell lymphoma. The author has an hindex of 17, co-authored 21 publications.
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Papers
Intratumoral injection of DNA encoding human interleukin 12 into patients with metastatic melanoma: clinical efficacy.
Lucie Heinzerling,Günter Burg,Reinhard Dummer,T Maier,Patrick A. Oberholzer,Jan Schultz,Lina Elzaouk,Jovan Pavlovic,Karin Moelling +8 more
TL;DR: Results show that intratumoral injection of DNA produced some beneficial clinical effect against various human cancers, and patients, in particular the clinical and local responders, exhibited an antigen-specific immune response against MAGE-1 and MART-1, which in some cases preexisted.
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Intralesional therapy with anti-CD20 monoclonal antibody rituximab in primary cutaneous B-cell lymphoma
TL;DR: Intralesional rituximab therapy is a nontoxic and effective treatment for cutaneous B-cell lymphoma that deserves further investigation in larger clinical trials.
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Tumor regression induced by intratumoral injection of DNA coding for human interleukin 12 into melanoma metastases in gray horses.
Lucie Heinzerling,Karsten Feige,Stefan Rieder,Margarete K. Akens,Reinhard Dummer,Gerald Stranzinger,Karin Moelling +6 more
TL;DR: The results demonstrate the effectiveness and safety of interleukin 12 encoding plasmid DNA therapy against established metastatic disease in a large animal model and serve as a basis for a clinical trial.
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Fucosyltransferase VII-Deficient Mice with Defective E-, P-, and L-Selectin Ligands Show Impaired CD4+ and CD8+ T Cell Migration into the Skin, but Normal Extravasation into Visceral Organs
Iris Erdmann,E. Paul Scheidegger,Frauke K. Koch,Lucie Heinzerling,Bernhard Odermatt,Günter Burg,John B. Lowe,Thomas M. Kündig +7 more
TL;DR: Interactions of selectins with their ligands are important for lymphocytes homing into the skin, but not for lymphocyte extravasation into visceral organs.
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Generalised Pustular Psoriasis Induced by Cyclosporin A Withdrawal Responding to the Tumour Necrosis Factor Alpha Inhibitor Etanercept
TL;DR: It is concluded that etanercept may be a safe and effective therapy not only in severe psoriatic arthritis, but also in cases of pustular rebound after withdrawal of immunosuppressive agents.
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