Lucia M. Mauro
University of Miami
34 Papers
563 Citations
Lucia M. Mauro is an academic researcher from University of Miami. The author has contributed to research in topics: Endothelium & Endothelial stem cell. The author has an hindex of 19, co-authored 34 publications.
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Papers
Effects of Severe Hypertension on Endothelial and Platelet Microparticles
Richard A. Preston,Wenche Jy,Joaquin J. Jimenez,Lucia M. Mauro,Lawrence L. Horstman,Madelyn Valle,Gerard Aime,Yeon S. Ahn +7 more
TL;DR: Because of the combined effects of endothelial and platelet microparticles on coagulation, leukocytes, and endothelium, it is possible that they may play a pathogenic role in mediating target organ injury in severe hypertension.
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Elevated plasma endothelial microparticles in multiple sclerosis.
Alireza Minagar,Wenche Jy,J. J. Jimenez,William A. Sheremata,Lucia M. Mauro,Wei Wei Mao,Lawrence L. Horstman,Yeon S. Ahn +7 more
TL;DR: Endothelial dysfunction is evident during exacerbation of MS, evidenced by shedding of EMP expressing PECAM-1 (CD31), and the in vitro data indicate contribution of one or more plasma factors in endothelial dysfunction of MS.
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Elevated endothelial microparticles in thrombotic thrombocytopenic purpura: findings from brain and renal microvascular cell culture and patients with active disease
TL;DR: TTP plasma activated and induced injury to MVECs in culture, judged by production of EMP and expression of activation markers, implying that it induced activation rather than apoptosis.
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Postprandial Hypertriglyceridemia Increases Circulating Levels of Endothelial Cell Microparticles
Alexandre C. Ferreira,Arley Peter,Armando J. Mendez,Joaquin J. Jimenez,Lucia M. Mauro,Julio A. Chirinos,Reyan Ghany,Salim S. Virani,Santiago Garcia,Lawrence L. Horstman,Joshua Purow,Wenche Jy,Yeon S. Ahn,Eduardo de Marchena +13 more
TL;DR: A single high-fat meal led to a significant elevation of plasma EMP levels in healthy, normolipidemic subjects and correlated with a postprandial elevation of serum triglycerides, suggesting EMPs may be an indirect marker of endothelial dysfunction or injury induced by postpr andial triglyceride-rich lipoproteins.
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Endothelial microparticles released in thrombotic thrombocytopenic purpura express von Willebrand factor and markers of endothelial activation.
TL;DR: Studies indicate endothelial activation in TTP, and EMP that co‐express VWF and CD62E could play a role in the pathogenesis of TTP.
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