Lucas Kipp
Stanford University
18 Papers
31 Citations
Lucas Kipp is an academic researcher from Stanford University. The author has contributed to research in topics: Medicine & Immunology. The author has an hindex of 4, co-authored 11 publications. Previous affiliations of Lucas Kipp include University College London & University of British Columbia.
Chat about Author
Papers
Clonally expanded B cells in multiple sclerosis bind EBV EBNA1 and GlialCAM
Tobias V. Lanz,Rebeccah Brewer,Peggy P. Ho,Jae Seung Moon,Kevin Jude,Daniel Fernandez,Ricardo A. Fernandes,Alejandro M. Gomez,Gabriel-Stefan Nadj,Christopher M. Bartley,Ryan D. Schubert,Isobel A. Hawes,Sara E. Vazquez,Manasi Iyer,J. Bradley Zuchero,Bianca Teegen,Jeffrey Dunn,Christopher Lock,Lucas Kipp,Victoria C. Cotham,Beatrix Ueberheide,Blake T. Aftab,Mark E. Anderson,Joseph L. DeRisi,Michael R. Wilson,Rachael Bashford-Rogers,Michael Platten,K. Christopher Garcia,Lawrence Steinman,William H. Robinson +29 more
TL;DR: In this paper , the authors demonstrate high-affinity molecular mimicry between the EBV transcription factor EBV nuclear antigen 1 (EBNA1) and the central nervous system protein glial cell adhesion molecule (GlialCAM) and provide structural and in vivo functional evidence for its relevance.
517
Clonally expanded B cells in multiple sclerosis bind EBV EBNA1 and GlialCAM
Tobias V. Lanz,R. Camille Brewer,Peggy P. Ho,Jae Seung Moon,Kevin Jude,Daniel Fernandez,Ricardo A. Fernandes,Alejandro M. Gomez,Gabriel-Stefan Nadj,Christopher M. Bartley,Ryan D. Schubert,Isobel A. Hawes,Sara E. Vazquez,Manasi Iyer,J. Bradley Zuchero,Bianca Teegen,Jeffrey Dunn,Christopher Lock,Lucas Kipp,Victoria C. Cotham,Beatrix Ueberheide,Blake T. Aftab,Mark E. Anderson,Joseph L. DeRisi,Michael R. Wilson,Rachael Bashford-Rogers,Michael Platten,K. Christopher Garcia,Lawrence Steinman,William H. Robinson +29 more
TL;DR: In this paper , the authors demonstrate high-affinity molecular mimicry between the EBV transcription factor EBV nuclear antigen 1 (EBNA1) and the central nervous system protein glial cell adhesion molecule (GlialCAM) and provide structural and in vivo functional evidence for its relevance.
447
KIR+CD8+ T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19
Jing Li,M. Zaslavsky,Yapeng Su,Jing Guo,Michael J. Sikora,Vincent van Unen,Asbjørn Christophersen,S. Chiou,Liang Chen,Jiefu Li,Xuhuai Ji,Julie Wilhelmy,Alana McSween,Brad A. Palanski,Venkata Vamsee Aditya Mallajosyula,Nathan A. Bracey,Gopal Krishna R. Dhondalay,Kartik Bhamidipati,Joy A. Pai,Lucas Kipp,Jeffrey Dunn,Stephen L. Hauser,Jorge R. Oksenberg,Ansuman T. Satpathy,William H. Robinson,Cornelia L. Dekker,Lars M. Steinmetz,Chaitan Khosla,Paul J. Utz,Ludvig M. Sollid,Yueh-hsiu Chien,James R. Heath,Nielsen Fernandez-Becker,Kari C. Nadeau,Naresha Saligrama,Mark M. Davis +35 more
TL;DR: It is found that CD8+ T cells expressing inhibitory killer cell immunoglobulin-like receptors (KIRs) are the human equivalent of Ly49+CD8+ regulatory T cells in mice and are increased in the blood and inflamed tissues of patients with a variety of autoimmune diseases.
Immunomodulatory receptors are differentially expressed in B and T cell subsets relevant to autoimmune disease.
Katherine A. Murphy,Kartik Bhamidipati,Samuel J S Rubin,Lucas Kipp,William H. Robinson,Tobias V. Lanz,Tobias V. Lanz +6 more
TL;DR: Three 23-colour flow cytometry panels for peripheral-blood T cells are designed, including 15 lineage-defining markers and 21 immunomodulatory cell-surface receptors, and a 22-marker panel for B cells, which revealed a subset of activated CD8+ T cells and unswitched memory B cells that are diminished in MS and SLE, respectively.
21
A case of GFAP-astroglial autoimmunity presenting with reversible parkinsonism
TL;DR: This case exemplifies the recently described neurologic syndrome of autoimmune GFAP astrocytopathy presenting with encephalomyelitis and parkinsonism, reversed by B lymphocyte depletion.
19