Luc Nicolas
Pasteur Institute
29 Papers
414 Citations
Luc Nicolas is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Wuchereria bancrofti & Bacillus sphaericus. The author has an hindex of 18, co-authored 29 publications. Previous affiliations of Luc Nicolas include Smith College.
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Papers
Real-Time PCR for Detection and Quantitation of Leishmania in Mouse Tissues
TL;DR: A highly accurate real-time PCR assay with which to reproducibly detect and quantify the relative Leishmania major burden in mouse tissue samples and is compatible with the clinical diagnosis of leishmaniasis.
Rapid differentiation of Old World Leishmania species by LightCycler polymerase chain reaction and melting curve analysis.
TL;DR: A LightCycler real-time polymerase chain reaction (PCR) assay has been developed to detect and differentiate four of the main Leishmania species of the Old World based on fluorescence melting curve analysis of PCR products generated from the minicircles of kinetoplast DNA.
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Cloning and expression of the first anaerobic toxin gene from Clostridium bifermentans subsp. malaysia, encoding a new mosquitocidal protein with homologies to Bacillus thuringiensis delta-endotoxins.
TL;DR: A gene (cbm71) encoding a 71,128-Da mosquitocidal protein was obtained by screening a size-fractionated XbaI digest of total genomic DNA from Clostridium bifermentans subsp.
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Reduction of Wuchereria bancrofti Adult Worm Circulating Antigen after Annual Treatments of Diethylcarbamazine Combined with Ivermectin in French Polynesia
TL;DR: Continuous reduction of CFA level after repeated treatments shows that elimination of W. bancrofti infection, monitored by CFA clearance, might be achieved within a few years with annual treatments of DEC combined with ivermectin.
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Persistence and recycling of Bacillus sphaericus 2362 spores in Culex quinquefasciatus breeding sites in West Africa
TL;DR: Projected costs of B. sphaericus formulation indicates that its use even at high dosages, would be more cost effective than the use of chemical insecticides, especially where c.
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