Lu-Ya Wang
Capital Medical University
40 Papers
92 Citations
Lu-Ya Wang is an academic researcher from Capital Medical University. The author has contributed to research in topics: Familial hypercholesterolemia & Medicine. The author has an hindex of 11, co-authored 34 publications. Previous affiliations of Lu-Ya Wang include Chinese Ministry of Education.
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Papers
The serum anion gap is associated with disease severity and all-cause mortality in coronary artery disease.
Shi-Wei Yang,Yujie Zhou,Yingxin Zhao,Yuyang Liu,Xiao-Fang Tian,Zhijian Wang,Dean Jia,Hongya Han,Bin Hu,Hua Shen,Fei Gao,Lu-Ya Wang,Jie Lin,Guo-Zhong Pan,Jian Zhang,Zhen-Feng Guo,Jie Du,Dayi Hu +17 more
TL;DR: A role for the serum AG in the risk-stratification of CAD is supported, as higher AG is associated with more severe clinical types of CAD and worse cardiac function, and the increased serum AG is an independent, significant, and strong predictor of all-cause mortality.
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Association between IL-1β, IL-8, and IL-10 polymorphisms and risk of acute pancreatitis.
TL;DR: Conditional logistic regression analyses showed that subjects carrying IL-10 -1082A/G and IL-8 -251 AA genotype with the A allele were significantly associated with an increased risk of acute pancreatitis, with adjusted odds ratio (95% confidence interval) of 1.01-3.31 and 1.02-1.90, respectively.
Functional characterization of two low-density lipoprotein receptor gene mutations in two Chinese patients with familial hypercholesterolemia.
TL;DR: It is found that these mutant LDLRs were defective in transport, which led to a reduction in cholesterol clearance, which increase the understanding of the mutational spectrum of FH in the Chinese population.
Characterization of the unique Chinese W483X mutation in the low-density lipoprotein–receptor gene in young patients with homozygous familial hypercholesterolemia
Long Jiang,Li-Yuan Sun,Xiao-Dong Pan,Pan-Pan Chen,Ling Tang,Wei Wang,Li-Min Zhao,Shi-Wei Yang,Lu-Ya Wang +8 more
TL;DR: The results suggest that younger HoFH patients with W483X mutations had a severe phenotype and should receive more aggressive treatment.
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Novel Approaches for the Treatment of Familial Hypercholesterolemia: Current Status and Future Challenges.
TL;DR: The current status of gene therapy and recent advances that will likely affect the clinical application of gene Therapy for the treatment of FH are discussed.
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