Lu Xing
18 Papers
4 Citations
Lu Xing is an academic researcher. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 2, co-authored 11 publications.
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Papers
Multiple functions of autophagy in vascular calcification
Xin Zhou,Suining Xu,Shu-Tong Yuan,Xinjuan Lei,Xiao-Ying Sun,Lu Xing,Hui-Jin Li,Chun-Xia He,Wei Qin,Dong Zhao,Peng-Quan Li,Edward Moharomd,Xuehong Xu,Hui-Ling Cao +13 more
TL;DR: The role of autophagy in vascular calcification is complex with many mechanistic unknowns as discussed by the authors, and the theoretical advantages of targeting autophagous cells as an intervention against cardiovascular calcification are discussed.
Role of Long Non-coding RNAs on Bladder Cancer.
Hui-Jin Li,Xue Gong,Zheng-Kun Li,Wei Qin,Chun-Xia He,Lu Xing,Xin Zhou,Dong Zhao,Hui-Ling Cao +8 more
TL;DR: In this article, the authors summarized the expression, function, molecular mechanisms and clinical significance of long non-coding RNAs on bladder cancer and provided promising novel biomarkers in early diagnosis, prognosis and monitoring of BC based on lncRNAs.
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New modification strategy of matrine as Hsp90 inhibitors based on its specific L conformation for cancer treatment.
Yiming Xu,Dewang Jing,Dong Zhao,Yongji Wu,Lu Xing,Haroon Ur Rashid,Haodong Wang,Lisheng Wang,Hui-Ling Cao +8 more
TL;DR: TSA (Thermal Shift Assay) results indicated that 21e, 22a-c and 22e-g exhibited strong binding force against Hsp90N with∣ΔTm∣ > 3, meanwhile, MTT assay also revealed these compounds displayed potent anticancer activity with IC50 values below 25 μM against HepG2, HeLa and MDA-MB-231 cells lines.
14
Atheroprotective Effects and Molecular Mechanism of Berberine
Lu Xing,Xin Zhou,Ai-Hong Li,Hui-Jin Li,Chun-Xia He,Wei Qin,Dong Zhao,Peng-Quan Li,Li Zhu,Hui-Ling Cao +9 more
TL;DR: In this paper, a review highlights the recent advances in understanding the anti-atherosclerosis mechanism of BBR and provides new ideas for atherosclerosis management, including attenuation of dyslipidemia, correction of endothelial dysfunction, inhibition of macrophage inflammation and foam cell formation.
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Nϵ-Carboxymethyl-Lysine Deteriorates Vascular Calcification in Diabetic Atherosclerosis Induced by Vascular Smooth Muscle Cell-Derived Foam Cells.
Suining Xu,Xin Zhou,Cun-Jun Zhu,Wei Qin,Jie Zhu,Ke-Lin Zhang,Hui-Jin Li,Lu Xing,Kun Lian,Cheng-Xiang Li,Zhen Sun,Zhongqun Wang,An-Ji Zhang,Hui-Ling Cao +13 more
TL;DR: It is concluded that CML promoted VSMC-derived foam cells calcification to aggravate VC in diabetic atherosclerosis, providing evidence for the contribution of foam cells to diabetic VC.
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