The invention relates to a diterpene indole compound crystal and an application thereof as an antitumor drug, wherein the diterpene indole compound crystal includes X-Ray single crystal diffraction data: a crystal system is an orthorhombic system, a space group is a space group P2[1]2[1]2[1], and cell parameters comprise a=12.11907(2) angstroms, b=13.2029(3) angstroms, c=15.3994(3) angstroms, alpha=90 DEG, beta=90 DEG, gamma=90 DEG, V=2624.00(8) cubic angstrom, Z=4, D[x]=1.142 mg/mm , F(000)=928, [mu](Cu K[alpha])=0.540 mm , the final deviation factor R[1]=0.05046, wR[2]=0.1067 [I>2[sigma](I)], and the Flack constant=0.0(2).

Diterpene indole compound crystal and application thereof as antitumor drug

The invention relates to an extraction method of a resin glycoside-type compound and belongs to the technical field of traditional Chinese medicines. The extraction method comprises carrying out chloroform-water heating backflow extraction on a medicinal sample, carrying out centrifugation precipitate removal orderly through methanol and chloroform, carrying out decoloring, carrying out silica gel column chromatography and gel chromatography purification, and carrying out drying. The invention provides the method for fast extraction of resin glycoside in convolvulaceous plants. The method has the advantages of simple operation, less solvent use amount, high purity and high yield and provides important reference for rapid purification of a resin glycoside-type compound.

Extraction method of resin glycoside-type compound

The invention relates to the technical field of medicine and particularly relates to sesquiterpene lactone compounds eut-Guaiane sesquiterpene with antibacterial activity and extracted from secondary metabolites of arctic eutypella funguses, and the chemical structural formula is as follows. The invention further provides a preparation method of the sesquiterpene lactone compounds and an application thereof in preparation of antibacterial agents.

Sesquiterpene lactone compounds with antibacterial activity and application thereof

The invention relates to the technical field of medicinal chemistry and particularly discloses a method for preparing cytochalasin H by using endophytic fungi in a mangrove forest The preparation method includes the following steps that S1, phomopsis liquidambari B3 strains of the endophytic fungi in the mangrove forest are inoculated to a sterilized culture medium; S2, culture is performed under the condition of the temperature of 25-35 DEG C for 5-30 days; S3, fermentation liquid and mycelium are separated; S4, separation and purification are conducted on the fermentation liquid and/or the mycelium to obtain the cytochalasin H The preparation method is simple and convenient, and the prepared cytochalasin H is high in content and is suitable for industrialized production

Method for preparing cytochalasin H by using endophytic fungi in mangrove forest

A carbidopa pharmaceutical composition and medical use thereof for treating liver cancer are provided. The carbidopa pharmaceutical composition provided in the present invention comprises carbidopa and a naturally produced compound (I) having a new structure and isolated from dry roots and stems of Notopterygium incisum. When used independently, carbidopa and the natural product has treatment effects on liver cancer. When the two are used in conjunction, the liver cancer treatment effects are further improved, which can be developed into medications for treating liver cancer.

Carbidopa pharmaceutical composition and medical use thereof for treating liver cancer

Diterpenoid compounds libertellenone G and libertellenone H with antineoplastic activities and application thereof

The invention relates to the field of medical technology. The structure formulas of three new Cytochalasin Z24, Cytochalasin Z25 and Cytochalasin Z26 extracted from secondary metabolite of the arctic eutypella fungus are shown in the specification. The invention further provides applications of Cytochalasin Z24, Cytochalasin Z25 and Cytochalasin Z26 in preparing anti-tumor drugs.

Cytochalasin Z24, Cytochalasin Z25 and Cytochalasin Z26 with anti-tumor activity, and applications thereof

The invention relates to the technical field of medicines and provides a novel glycoside compound separated from radix glehniae. The compound has the following structural formula as shown in the specification. The invention also provides a preparation method of the glycoside compound and an application of the glycoside compound in the preparation of anti-inflammatory drugs.

Glycoside compound contained in radix glehniae as well as preparation method and application thereof

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Diterpenoid compounds libertellenone G and libertellenone H with antineoplastic activities and application thereof

Cytochalasin Z24, Cytochalasin Z25 and Cytochalasin Z26 with anti-tumor activity, and applications thereof

Sesquiterpene lactone compounds with antibacterial activity and application thereof

Glycoside compound contained in radix glehniae as well as preparation method and application thereof