Lu-Ping Liu
Harvard University
5 Papers
25 Citations
Lu-Ping Liu is an academic researcher from Harvard University. The author has contributed to research in topics: RNA interference & CRISPR. The author has an hindex of 3, co-authored 5 publications. Previous affiliations of Lu-Ping Liu include Howard Hughes Medical Institute.
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Papers
A Drosophila Resource of Transgenic RNAi Lines for Neurogenetics
Jian-Quan Ni,Lu-Ping Liu,Richard Binari,Robert Hardy,Hye-Seok Shim,Amanda Cavallaro,Matthew A. Booker,Barret D. Pfeiffer,Michele Markstein,Haiyan Wang,Christians Villalta,Todd R. Laverty,Lizabeth A. Perkins,Lizabeth A. Perkins,Norbert Perrimon +14 more
TL;DR: The efficacy of VALIUM as a vector to analyze the phenotype of genes expressed in the nervous system and a library of 2282 constructs targeting 2043 genes that will be particularly useful for studies of the nervousSystem as they target, in particular, transcription factors, ion channels, and transporters are documented.
Optimized strategy for in vivo Cas9-activation in Drosophila.
Benjamin Scott Ewen-Campen,Donghui Yang-Zhou,Vitória R. Fernandes,Vitória R. Fernandes,Delfina P. González,Delfina P. González,Lu-Ping Liu,Lu-Ping Liu,Rong Tao,Xingjie Ren,Jin Sun,Yanhui Hu,Jonathan Zirin,Stephanie E. Mohr,Jian-Quan Ni,Norbert Perrimon +15 more
TL;DR: It is shown that CRISPRa leads to physiologically relevant levels of target gene expression capable of generating strong gain-of-function (GOF) phenotypes in multiple tissues and thus serves as a useful platform for genetic screening.
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Large-Scale Transgenic Drosophila Resource Collections for Loss- and Gain-of-Function Studies.
Jonathan Zirin,Yanhui Hu,Lu-Ping Liu,Donghui Yang-Zhou,Ryan Colbeth,Dong Yan,Benjamin Scott Ewen-Campen,Rong Tao,Eric Vogt,Sara VanNest,Cooper Cavers,Christians Villalta,Aram Comjean,Jin Sun,Xia Wang,Yu Jia,Ruibao Zhu,Ping Peng,Jinchao Yu,Da Shen,Yuhao Qiu,Limmond Ayisi,Henna Ragoowansi,Ethan Fenton,Senait Efrem,Annette L. Parks,Kuniaki Saito,Shu Kondo,Liz Perkins,Stephanie E. Mohr,Jian-Quan Ni,Norbert Perrimon,Norbert Perrimon +32 more
TL;DR: The Transgenic RNAi Project (TRiP), a Drosophila melanogaster functional genomics platform at Harvard Medical School, was initiated in 2008 to generate and distribute a genome-scale collection of RNA interference (RNAi) fly stocks, and this work presents an update on these libraries of publicly available RNAi and CRISPR fly stocks.
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Perspectives on gene expression regulation techniques in Drosophila.
Rong-Gang Xu,Xia Wang,Da Shen,Jin Sun,Huan-Huan Qiao,Fang Wang,Lu-Ping Liu,Jian-Quan Ni,Jian-Quan Ni +8 more
TL;DR: The main purpose of this review is to provide the fly research community with an updated summary of newly developed gene expression regulation techniques and help the community to select appropriate methods and optimize the research strategy.
7
Large-scale transgenic Drosophila resource collections for loss- and gain-of-function studies
Jonathan Zirin,Yanhui Hu,Lu-Ping Liu,Donghui Yang-Zhou,Ryan Colbeth,Dong Yan,Benjamin Scott Ewen-Campen,Rong Tao,Eric Vogt,Sara VanNest,Cooper Cavers,Christians Villalta,Aram Comjean,Jin Sun,Xia Wang,Yu Jia,Ruibao Zhu,Ping Peng,Jinchao Yu,Da Shen,Yuhao Qiu,Limmond Ayisi,Henna Ragoowansi,Ethan Fenton,Senait Efrem,Annette L. Parks,Kuniaki Saito,Shu Kondo,Liz Perkins,Stephanie E. Mohr,Jian-Quan Ni,Norbert Perrimon,Norbert Perrimon +32 more
TL;DR: The Transgenic RNAi Project (TRiP), a Drosophila functional genomics platform at Harvard Medical School, was initiated in 2008 to generate and distribute a genome-scale collection of RNAi fly stocks, and this work presents an update on these libraries of publicly available RNAi and CRISPR fly stocks.