Lu Liu
6 Papers
1 Citations
Lu Liu is an academic researcher. The author has contributed to research in topics: Biology & Gene. The author has an hindex of 1, co-authored 2 publications.
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Papers
Gut microbial genomes with paired isolates from China illustrate probiotic and cardiometabolic effects.
Quanbin Dong,Yifeng Wang,Yunfan Tian,Shunhe Wang,Chengcheng Zhang,Leilei Yu,Fengwei Tian,Xiaoxiang Gao,Hang Guo,Shanrong Yi,Mingyang Li,Yang Liu,Qingsong Zhang,Wenwei Lu,Gang Wang,Bo Yang,Shumao Cui,Dongxu Hua,Xiuchao Wang,Yuwen Jiao,Lu Liu,Qiufeng Deng,Tingting Wu,Huayiyang Zou,Jing Shi,Haifeng Zhang,Daming Fan,Yanhui Sheng,Jianxin Zhao,Hao Zhang,Wei Sun,Wei Chen,Xiangqing Kong,Lianmin Chen,Qixiao Zhai +34 more
TL;DR: The Chinese Gut Microbial Reference set is presented, comprising 101,060 high-quality metagenomic assembled genomes of 3,707 nonredundant species from 3,234 fecal samples across primarily rural Chinese locations, and 987 novel species relative to worldwide databases.
6
Early microbial intervention reshapes phenotypes of newborn Bos taurus through metabolic regulations
Yizhao Shen,Yan Li,Tingting Wu,Quanbin Dong,Qiufeng Deng,Lu Liu,Yanfei Guo,Yufeng Cao,Qiufeng Li,Jing Shi,Huayiyang Zou,Yuwen Jiao,Luoyang Ding,Jianguo Li,Yanxia Gao,Shixian Hu,Yifeng Wang,Lianmin Chen +17 more
TL;DR: A metagenomic and metabolomic atlas of the temporal development of the gut microbiome in newborn calves shows that early microbial transplantation can alter the gut microbiome of newborns, leading to improved physiological status and later milk production.
4
Temporal colonization and metabolic regulation of the gut microbiome in neonatal oxen at single nucleotide resolution
Quanbin Dong,Dongxu Hua,Xiuchao Wang,Yuwen Jiao,Lu Liu,Qiufeng Deng,Tingting Wu,Huayiyang Zou,Chen Zhao,Chengkun Wang,Jiafa Reng,Luoyang Ding,Shixian Hu,Jing Shi,Yifeng Wang,Haifeng Zhang,Yanhui Sheng,Wei Sun,Yizhao Shen,Liming Tang,Xiangqing Kong,Lianmin Chen +21 more
TL;DR: The current results indicate that temporal colonization and transplantation-driven strain replacement are crucial for newborn gut development, offering insights for enhancing newborn health and growth.
3
A Host-Harbored Metabolic Susceptibility of Coronavirus Enables Broad-Spectrum Targeting
Huan Fang,Yonglun Wang,Lu Liu,Kunlun Cheng,Pei Li,Ya Tan,Xingjie Hao,Miao Mei,Xinxuan Xu,Yuanhang Yao,Fuwen Zan,Yuangang Zhu,Bolin Xu,Dong Huang,Chaolong Wang,Xu Tan,Zhaohui Qian,Xiaowei Chen +17 more
TL;DR: In this article , the authors show that the master lipid regulator SREBP1 couples the phospholipid scramblase TMEM41B to constitute a host "metabolism-to-manufacture" cascade that maximizes membrane supplies to support coronaviral genome replication, harboring biosynthetic enzymes including Lipin1 as druggable VSE host genes.
2
Temporal colonization of the gut microbiome in neonatal Bos taurus at single nucleotide resolution
Quanbin Dong,Dongxu Hua,Xiuchao Wang,Yuwen Jiao,Lu Liu,Qiufeng Deng,Tingting Wu,Huayiyang Zou,L. Y. Ding,Shixian Hu,Jing Shi,Yifeng Wang,Haifeng Zhang,Yanhui Sheng,Wei Sun,Yizhao Shen,Liming Tang,Xiangqing Kong,Lianmin Chen +18 more
TL;DR: Wang et al. as mentioned in this paper found that microbial genetic variations may influence the health status and growth performance of neonatal calves by modulating metabolites via structural regulation of their encoded proteins, which enabled them to characterize 24 study-wide significant associations (P < 4.4×10−9).