Lu Gao
University of Cambridge
7 Papers
21 Citations
Lu Gao is an academic researcher from University of Cambridge. The author has contributed to research in topics: Intima-media thickness & Population. The author has an hindex of 6, co-authored 7 publications.
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Papers
Carotid intima-media thickness progression to predict cardiovascular events in the general population (the PROG-IMT collaborative project): a meta-analysis of individual participant data.
Matthias W. Lorenz,Joseph F. Polak,Maryam Kavousi,Ellisiv B. Mathiesen,Henry Völzke,Tomi-Pekka Tuomainen,Dirk Sander,Matthieu Plichart,Alberico L. Catapano,Christine Robertson,Stefan Kiechl,Tatjana Rundek,Moïse Desvarieux,Moïse Desvarieux,Moïse Desvarieux,Lars Lind,Caroline Schmid,Pronabesh DasMahapatra,Lu Gao,Kathrin Ziegelbauer,Michiel L. Bots,Michiel L. Bots,Simon G. Thompson +22 more
TL;DR: The association between cIMT progression assessed from two ultrasound scans and cardiovascular risk in the general population remains unproven and no conclusion can be derived for the use of c IMT progression as a surrogate in clinical trials.
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Carotid Intima-Media Thickness Progression as Surrogate Marker for Cardiovascular Risk: Meta-Analysis of 119 Clinical Trials Involving 100 667 Patients
Peter Willeit,Lena Tschiderer,Elias Allara,Kathrin Reuber,Lisa Seekircher,Lu Gao,Ximing Liao,Eva Lonn,Hertzel C. Gerstein,Salim Yusuf,Frank P. Brouwers,Folkert W. Asselbergs,Wiek H. van Gilst,Sigmund A. Anderssen,Diederick E. Grobbee,John J.P. Kastelein,Frank L.J. Visseren,George Ntaios,Apostolos I. Hatzitolios,Christos Savopoulos,Pythia T. Nieuwkerk,Erik S.G. Stroes,Matthew Walters,Peter Higgins,Jesse Dawson,Paolo Gresele,Giuseppe Guglielmini,Rino Migliacci,Marat V. Ezhov,Maya S. Safarova,T.V. Balakhonova,Eiichi Sato,Mayuko Amaha,Tsukasa Nakamura,Kostas Kapellas,Lisa Jamieson,Michael R. Skilton,James A. Blumenthal,Alan L. Hinderliter,Andrew Sherwood,Patrick Smith,Michiel A. Van Agtmael,Peter Reiss,Marit G.A. Van Vonderen,Stefan Kiechl,Gerhard Klingenschmid,Matthias Sitzer,Coen D.A. Stehouwer,Heiko Uthoff,Zhiyong Zou,Ana Rosa Cunha,Mario Fritsch Neves,Miles D. Witham,Hyun Woong Park,Moo Sik Lee,Jang Ho Bae,Enrique Bernal,K. Wachtell,Sverre E. Kjeldsen,Michael H. Olsen,David Preiss,Naveed Sattar,Edith Beishuizen,Menno V. Huisman,Mark A. Espeland,Caroline Schmidt,Stefan Agewall,Ercan Ok,Gulay Asci,Eric de Groot,Muriel P.C. Grooteman,Peter J. Blankestijn,Michiel L. Bots,Michael J. Sweeting,Simon G. Thompson,Matthias W. Lorenz +75 more
TL;DR: The extent of intervention effects on cIMT progression predicted the degree of CVD risk reduction, providing a missing link supporting the usefulness of cIMt progression as a surrogate marker for CVDrisk in clinical trials.
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Predictive value for cardiovascular events of common carotid intima media thickness and its rate of change in individuals at high cardiovascular risk - Results from the PROG-IMT collaboration
Matthias W. Lorenz,Lu Gao,Kathrin Ziegelbauer,Giuseppe Danilo Norata,Jean Philippe Empana,Irene Schmidtmann,Hung-Ju Lin,Stela McLachlan,Lena Bokemark,Kimmo Ronkainen,Mauro Amato,Ulf Schminke,Sathanur R. Srinivasan,Lars Lind,Shuhei Okazaki,Coen D.A. Stehouwer,Peter Willeit,Joseph F. Polak,Helmuth Steinmetz,Dirk Sander,Holger Poppert,Moïse Desvarieux,M. Arfan Ikram,Stein Harald Johnsen,Daniel Staub,Cesare R. Sirtori,Bernhard Iglseder,Oscar Beloqui,Gunnar Engström,Alfonso Friera,Francesco Rozza,Wuxiang Xie,Grace Parraga,Liliana Grigore,Matthieu Plichart,Stefan Blankenberg,Stefan Blankenberg,Ta-Chen Su,Caroline Schmidt,Tomi-Pekka Tuomainen,Fabrizio Veglia,Henry Völzke,Giel Nijpels,Johann Willeit,Ralph L. Sacco,Oscar H. Franco,Heiko Uthoff,Bo Hedblad,Carmen Suárez,Raffaele Izzo,Dong Zhao,Thapat Wannarong,Thapat Wannarong,Alberico L. Catapano,Pierre Ducimetière,Christine Espinola-Klein,Kuo-Liong Chien,Jackie F. Price,Göran Bergström,Jussi Kauhanen,Elena Tremoli,Marcus Dörr,Gerald S. Berenson,Kazuo Kitagawa,Jacqueline M. Dekker,Stefan Kiechl,Matthias Sitzer,Horst Bickel,Tatjana Rundek,Albert Hofman,Ellisiv B. Mathiesen,Samuela Castelnuovo,Manuel F. Landecho,Maria Rosvall,Rafael Gabriel,Nicola De Luca,Jing Liu,Damiano Baldassarre,Maryam Kavousi,Eric de Groot,Michiel L. Bots,David Yanez,Simon G. Thompson +82 more
TL;DR: It is confirmed that common CIMT is associated with future CVD events in individuals at high risk andCIMT change does not relate to future event risk in high-risk individuals.
Progression of conventional cardiovascular risk factors and vascular disease risk in individuals: insights from the PROG-IMT consortium:
Martin Bahls,Matthias W. Lorenz,Marcus Dörr,Lu Gao,Kazuo Kitagawa,Tomi-Pekka Tuomainen,Stefan Agewall,Stefan Agewall,Gerald S. Berenson,Alberico L. Catapano,Giuseppe Danilo Norata,Michiel L. Bots,Wiek H. van Gilst,Folkert W. Asselbergs,Folkert W. Asselbergs,Frank P. Brouwers,Heiko Uthoff,Dirk Sander,Holger Poppert,Michael H. Olsen,Jean Philippe Empana,Ulf Schminke,Damiano Baldassarre,Fabrizio Veglia,Oscar H. Franco,Oscar H. Franco,Maryam Kavousi,Eric de Groot,Ellisiv B. Mathiesen,Liliana Grigore,Joseph F. Polak,Tatjana Rundek,Coen D.A. Stehouwer,Michael R. Skilton,Apostolos I. Hatzitolios,Christos Savopoulos,George Ntaios,Matthieu Plichart,Stela McLachlan,Lars Lind,Peter Willeit,Helmuth Steinmetz,Moïse Desvarieux,Moïse Desvarieux,M. Arfan Ikram,M. Arfan Ikram,Stein Harald Johnsen,Caroline Schmidt,Johann Willeit,Pierre Ducimetière,Jackie F. Price,Göran Bergström,Jussi Kauhanen,Stefan Kiechl,Matthias Sitzer,Horst Bickel,Ralph L. Sacco,Albert Hofman,Albert Hofman,Henry Völzke,Simon G. Thompson +60 more
TL;DR: In this paper, an individual participant meta-analysis was used to associate the annualised progression of systolic blood pressure, total cholesterol, low-density lipoprotein cholesterol, and high-density cholesterol with future cardiovascular disease risk in 13 prospective cohort studies.
Abdominal aortic aneurysm. Comparing studies for cost effectiveness of screening.
TL;DR: It is concluded that screening men aged 65 for abdominal aortic aneurysm is not cost effective and this conclusion conflicts with that of the 10 year follow-up of the randomised Multicentre Aneurysm Screening Study (MASS).