Lu Chen
Chongqing Medical University
5 Papers
19 Citations
Lu Chen is an academic researcher from Chongqing Medical University. The author has contributed to research in topics: Copy-number variation & Human leukocyte antigen. The author has an hindex of 5, co-authored 5 publications.
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Papers
Genetic Variations of IL17F and IL23A Show Associations with Behçet’s Disease and Vogt-Koyanagi-Harada Syndrome
Shengping Hou,Dan Liao,Jun Zhang,Jing Fang,Lu Chen,Jian Qi,Qi Zhang,Yunjia Liu,Lin Bai,Yan Zhou,Aize Kijlstra,Peizeng Yang +11 more
TL;DR: High gene copy numbers of IL17F and IL23A were associated with BD and VKH syndrome and enhancedIL17F protein production and PBMC proliferation wereassociated with high IL17f copy numbers.
41
TRAF5 and TRAF3IP2 gene polymorphisms are associated with Behçet's disease and Vogt-Koyanagi-Harada syndrome: a case-control study.
Qin Xiang,Lu Chen,Shengping Hou,Jing Fang,Yan Zhou,Lin Bai,Yunjia Liu,Aize Kijlstra,Peizeng Yang +8 more
TL;DR: Evidence is provided that TRAF5 and TRAF3IP2 genes are involved in the development of Behçet's disease and VKH syndrome.
Association Between Copy Number Variations of TLR7 and Ocular Behcet's Disease in a Chinese Han Population
Jing Fang,Lu Chen,Jihong Tang,Shengping Hou,Dan Liao,Zi Ye,Chaokui Wang,Qinfeng Cao,Aize Kijlstra,Peizeng Yang +9 more
TL;DR: Evidence that a high copy number of TLR7 confers risk for BD in a Chinese Han population is provided, providing evidence that gene copy number variations of Toll-like receptors are associated with uveitis.
20
High C4 gene copy numbers protects against Vogt-Koyanagi-Harada syndrome in Chinese Han
TL;DR: Findings indicate a decreased expression of serum C4 and a decreased frequency of high C4 gene copy number in patients with VKH, and a significant positive association between C4 expression with C4 CNVs.
19
TNF receptor-associated factor 5 gene confers genetic predisposition to acute anterior uveitis and pediatric uveitis.
Qin Xiang,Lu Chen,Jing Fang,Shengping Hou,Lin Wei,Lin Bai,Yunjia Liu,Yan Zhou,Aize Kijlstra,Peizeng Yang +9 more
TL;DR: It is revealed that TRAF5 is involved in the development of AAU and pediatric uveitis and stratified analysis according to the clinical and laboratory observations suggested that rs12569232/TRAF5 may play a role in theDevelopment of retinal vasculitis.