8 Papers
50 Citations
Lu Chen is an academic researcher from University of California, Irvine. The author has contributed to research in topics: Transplantation & Kinase. The author has an hindex of 6, co-authored 8 publications. Previous affiliations of Lu Chen include Albert Einstein College of Medicine & Loyola University Chicago.
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Papers
Properties, regulation, and in vivo functions of a novel protein kinase D: Caenorhabditis elegans DKF-2 links diacylglycerol second messenger to the regulation of stress responses and life span.
TL;DR: The results suggest a mechanism for increased longevity and show that a PKD links DAG signals to regulation of stress responses and life span.
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Neuronal and Intestinal Protein Kinase D Isoforms Mediate Na+ (Salt Taste)–Induced Learning
TL;DR: It is shown that pathways containing EGL-8–TPA-1–DKF-2 enable learning and behavioral plasticity by receiving, transmitting, and cooperatively integrating environmental signals targeted to both neurons and intestine.
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Intraspinal Transplantation of Mouse and Human Neural Precursor Cells
Jason G. Weinger,Lu Chen,Ronald Coleman,Ronika Leang,Warren C. Plaisted,Jeanne F. Loring,Thomas E. Lane +6 more
TL;DR: Transplantation of neural precursor cells into the spinal cord is an efficacious way to determine their effects in neurological disorders such as multiple sclerosis, Alzheimer's disease, and spinal cord injury.
Intraspinal Transplantation of Human Neural Stem Cells
Lu Chen,Kevin S. Carbajal,Jason G. Weinger,Ronald Coleman,Thomas E. Lane +4 more
- 01 Jan 2012
TL;DR: In this chapter, a detailed procedure for intraspinal transplantation of human NPCs including information on cell preparation as well as surgical procedures on mice that enable a successful transplant are provided.
Transgenic CaMKIIδC Overexpression Uniquely Alters Cardiac Myocyte Ca2+ Handling. Reduced SR Ca2+ Load and Activated SR Ca2+ Release
TL;DR: It is concluded that CaMKII&dgr;C overexpression causes acute modulation of excitation-contraction coupling, which contributes to heart failure.