Lothar Rink
RWTH Aachen University
262 Papers
1.1K Citations
Lothar Rink is an academic researcher from RWTH Aachen University. The author has contributed to research in topics: Zinc & Immune system. The author has an hindex of 63, co-authored 235 publications. Previous affiliations of Lothar Rink include University of Lübeck & Laval University.
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Papers
Immunotoxicity Monitoring in a Population Exposed to Polychlorinated Biphenyls.
Hajo Haase,Astrid V. Fahlenkamp,Thomas Schettgen,André Esser,Monika Gube,Patrick Ziegler,Thomas Kraus,Lothar Rink +7 more
TL;DR: There were several effects on the cellular composition of adaptive immunity, affecting both T- and B-cells, however, the values were not generally outside the reference ranges for healthy adult individuals and did not indicate overt functional immunodeficiency, even in subjects with the uppermost PCB burden.
Surveillance program for former PCB-exposed workers of a transformer and capacitor recycling company, family members, employees of surrounding companies, and area residents--executive summary.
Thomas Kraus,Monika Gube,Jessica Lang,André Esser,Walter Sturm,Bruno Fimm,Klaus Willmes,Joseph Neulen,Jens M. Baron,Hans F. Merk,Thomas Schettgen,Kerstin Konrad,Sabine Deisz,Lothar Rink,Michael Hagmann,Birgit Fillies,Wolfgang Zschiesche,Jürgen Wittsiepe,Michael Wilhelm +18 more
TL;DR: In a German company polychlorinated biphenyls (PCB)-containing transformers and capacitors were recycled on a large scale, human biomonitoring revealed a high PCB body burden in workers of the recycling company, in surrounding locations of this plant, in companies in the neighborhood ofThis plant, and in family members of these employees.
Proton-Pump Inhibitors Suppress T Cell Response by Shifting Intracellular Zinc Distribution
TL;DR: In this article , the authors analyzed the T cell response after treatment with Pantoprazole in vitro and found that the pre-incubation of T cells with either PHA-L or toxic shock syndrome toxin-1 (TSST-1) reduced the production and secretion of interferon (IFN)-γ and interleukin (IL)-2 after the T cells were activated with phytohemagglutinin (PHA)-L.
Selection of an inadequate housekeeping gene leads to misinterpretation of target gene expression in zinc deficiency and zinc supplementation models
Veronika Kloubert,Lothar Rink +1 more
TL;DR: The importance of choosing adequate housekeeping genes, which might comprise the use of more than one housekeeping gene when different conditions are tested, such as zinc deficiency and zinc supplementation, is highlighted.
Leucocyte response and anti-inflammatory cytokines in community acquired pneumonia
TL;DR: Results indicate that PMN may be responsible for the increase in anti-inflammatory cytokines in CAP and strategies to increase neutrophil counts may exert beneficial effects, not only by augmenting the antimicrobial activity but also by modulating the inflammatory cytokine response.