Lothar Rink
RWTH Aachen University
262 Papers
1.1K Citations
Lothar Rink is an academic researcher from RWTH Aachen University. The author has contributed to research in topics: Zinc & Immune system. The author has an hindex of 63, co-authored 235 publications. Previous affiliations of Lothar Rink include University of Lübeck & Laval University.
Chat about Author
Papers
Influence of DNA-methylation on zinc homeostasis in myeloid cells: Regulation of zinc transporters and zinc binding proteins.
TL;DR: Data indicate that DNA methylation is an important epigenetic mechanism affecting zinc binding proteins and transporters, and, therefore, regulating zinc homeostasis in myeloid cells.
Calculating zinc uptake by Zinc-APP.
TL;DR: In this article , co-exposure to sulphur dioxide and fluoride exacerbated enamel damage, resulting in more severe enamel defects of incisor and the damage occurred earlier, and the results indicate that co-expposure to SO2 and fluoride may result in more toxicity both in vitro and in vivo than a single exposure to SO 2 and fluoride, suggesting that residents in areas contaminated with SO2, fluoride may be more likely to suffer enamel damages.
Cytokine production of neutrophils is limited to interleukin‐8
TL;DR: The results show that granulocytes have a preformed capacity to produce the cytokine IL‐8 and that the production of proinflammatory cytokines by neutrophils is limited to IL‐ 8.
Zinc supplementation induces regulatory T cells by inhibition of Sirt-1 deacetylase in mixed lymphocyte cultures.
Eva Rosenkranz,Claudia H.D. Metz,Martina Maywald,Ralf-Dieter Hilgers,Inga Weßels,Tina Senff,Hajo Haase,Hajo Haase,Maximilian Jager,Melanie Ott,Richard Aspinall,Birgit Plümäkers,Lothar Rink +12 more
TL;DR: Zinc should be considered to prevent graft-versus-host disease (GVHD) as it is capable of stabilizing iTregs, resulting in increased numbers of this cell type while not suppressing the immune system.
Zinc homeostasis and immunosenescence.
Martina Maywald,Lothar Rink +1 more
TL;DR: An impaired function of innate immune cells indicate a predominance of zinc deficiency in the elderly that may contribute to immunosenescence, and current findings about zinc deficiency and supplementation in elderly individuals are summarized.