Lothar Rink
RWTH Aachen University
262 Papers
1.1K Citations
Lothar Rink is an academic researcher from RWTH Aachen University. The author has contributed to research in topics: Zinc & Immune system. The author has an hindex of 63, co-authored 235 publications. Previous affiliations of Lothar Rink include University of Lübeck & Laval University.
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Papers
Zinc status, psychological and nutritional assessment in old people recruited in five European countries: Zincage study.
Fiorella Marcellini,Cinzia Giuli,Roberta Papa,Cristina Gagliardi,George Dedoussis,George Herbein,Tamas Fulop,Daniela Monti,Lothar Rink,Jolanta Jajte,Eugenio Mocchegiani +10 more
TL;DR: A relationship between marginal zinc deficiency and impaired psychological dimensions occurred in Greece than in other European countries due to low intake and less variety of foods rich of zinc.
Effect of zinc supplementation on plasma IL-6 and MCP-1 production and NK cell function in healthy elderly: interactive influence of +647 MT1a and -174 IL-6 polymorphic alleles.
Erminia Mariani,Simona Neri,Luca Cattini,Eugenio Mocchegiani,Marco Malavolta,George Dedoussis,Stavroula Kanoni,Lothar Rink,Jolanta Jajte,Andrea Facchini +9 more
TL;DR: An interactive effect of polymorphic alleles of MT1a and IL-6 genes on zinc, IL- 6, MCP-1 and NK activity was evidenced following supplementation, indicating the genetic background as one of the determinants for identifying groups of subjects that can take advantage of therapeutic intervention.
The Intracellular Free Zinc Level Is Vital for Treg Function and a Feasible Tool to Discriminate between Treg and Activated Th Cells.
TL;DR: It is hypothesized that the intracellular free zinc level in Th cells is essential in guaranteeing proper cellular function and can be used to discriminate Tregs from other Th cell subsets.
Intracellular zinc during cell activation and zinc deficiency.
TL;DR: In this paper, the impact of cellular priming due to stimulation with interleukin (IL)-1, IL-2, IL 4, IL 6 or the chemokine CXCL12a and its subsequent influence on the intracellular free zinc concentration was examined.
•Journal Article
Induction of cytokines by zinc ions in human peripheral blood mononuclear cells and separated monocytes.
TL;DR: The data suggest that zinc acts primarily on monocytes by inducing monokine secretion and that T-cell activation represents a secondary effect in the cytokine cascade.