Lothar Rink
RWTH Aachen University
262 Papers
1.1K Citations
Lothar Rink is an academic researcher from RWTH Aachen University. The author has contributed to research in topics: Zinc & Immune system. The author has an hindex of 63, co-authored 235 publications. Previous affiliations of Lothar Rink include University of Lübeck & Laval University.
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Papers
Zinc deficiency impairs interferon-γ production on post-transcriptional level.
TL;DR: A strong post-transcriptional effect of zinc on interferon-γ is hypothesize, based on results and the latest research, which is the first about this unconventional ratio of IFN-γ mRNA to protein.
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Cadmium ions promote monocytic differentiation of human leukemia HL-60 cells treated with 1α,25-dihydroxyvitamin D3
TL;DR: Cadmium can augment monocytic differentiation by activating ERK1/2 signaling, leading to increased generation of functional monocytes, which could contribute to the impact of cadmium on the immune system owing to their role in the production of pro-inflammatory cytokines and activation of T-cells by antigen presentation.
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Activation of IL-1β and TNFα genes is mediated by the establishment of permissive chromatin structures during monopoiesis.
Inga Wessels,Eva Rosenkranz,Mónica S. Ventura Ferreira,Sabine Neuss,Martin Zenke,Lothar Rink,Peter Uciechowski +6 more
TL;DR: The participation of acetylation in IL-1β and TNFα promoter activation shed new light on the regulation of IL- 1β or TNF α expression and may have implications for understanding the progression from normal to disease conditions.
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UK Food Standards Agency Workshop Report: Diet and Immune Function
Peter Sanderson,Rachel L. Elsom,Verity Kirkpatrick,Philip C. Calder,Jayne V. Woodside,Elizabeth A. Williams,Lothar Rink,Susan J. Fairweather-Tait,Kamal Ivory,Margherita T. Cantorna,Bernhard Watzl,Elaine Stone +11 more
TL;DR: The workshop highlighted the need to further clarify the potential public health relevance of observed nutrition-related changes in immune function, e.g. susceptibility to infections and infectious morbidity.
The Interaction of Sodium and Zinc in the Priming of T Cell Subpopulations Regarding Th17 and Treg Cells.
TL;DR: Zinc induced the number of regulatory T cells (Treg) and decreased T helper 17 cells (Th17) and sodium had the opposite effect and zinc declined Zip10 mRNA expression while sodium induced it, whereas MT-1 mRNA expression was induced by zinc while it was reduced by sodium.
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