Lothar Rink
RWTH Aachen University
262 Papers
1.1K Citations
Lothar Rink is an academic researcher from RWTH Aachen University. The author has contributed to research in topics: Zinc & Immune system. The author has an hindex of 63, co-authored 235 publications. Previous affiliations of Lothar Rink include University of Lübeck & Laval University.
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Papers
In situ hybridization of the mRNA for interferon-γ, interferon-αE, interferon-β, interleukin-1β and interleukin-6 and characterization of infiltrating cells in thyroid tissues
TL;DR: The data suggest that the application of in situ hybridization with antisense RNA permits the study of cytokine production in tissues of both autoimmune and non-autoimmune origin.
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•Journal Article
Interferon-gamma plays a key role in the human mixed lymphocyte culture.
TL;DR: It is concluded that measurement of IFN-gamma might be a new and more sensitive parameter for BMT than the established proliferation assay, since IFN -gamma directly quantifies T cell activation.
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Effect of ZIP2 Gln/Arg/Leu (rs2234632) polymorphism on zinc homeostasis and inflammatory response following zinc supplementation.
Robertina Giacconi,Laura Costarelli,Marco Malavolta,Maurizio Cardelli,Roberta Galeazzi,Francesco Piacenza,Nazzarena Gasparini,Andrea Basso,Erminia Mariani,Tamas Fulop,Lothar Rink,George Dedoussis,Georges Herbein,Jolanta Jajte,Mauro Provinciali,Franco Busco,Eugenio Mocchegiani +16 more
TL;DR: New evidence is provided on the effect of ZIP2 Gln/Arg/Leu polymorphism on proinflammatory mediators and zinc homeostasis in elderly population with a more pronounced anti-inflammatory effect of zinc supplementation in subjects carrying ZIP2 Leu- (Arg43Arg) genotype.
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Human Neutrophils Produce Macrophage Inhibitory Protein-1β but Not Type I Interferons in Response to Viral Stimulation
TL;DR: It is concluded that neutrophils fail to prevent viral infection by IFN production but probably possess alternative mechanisms, such as secreting MIP-1beta in response to viruses.
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