Lothar Rink
RWTH Aachen University
262 Papers
1.1K Citations
Lothar Rink is an academic researcher from RWTH Aachen University. The author has contributed to research in topics: Zinc & Immune system. The author has an hindex of 63, co-authored 235 publications. Previous affiliations of Lothar Rink include University of Lübeck & Laval University.
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Papers
No detectable effects of Acute Tryptophan Depletion on Short-Term Immune System Cytokine Levels in Healthy Adults
Caroline S. Hildebrandt,K. Helmbold,Maike Linden,Karl-Josef Langen,Karl-Josef Langen,Christian Filss,Kevin C. Runions,Kevin C. Runions,Richard M. Stewart,Pradeep Rao,Pradeep Rao,Julie K. Moore,Julie K. Moore,Simone Mahfouda,Simone Mahfouda,Hugo A.E. Morandini,Janice W. Y. Wong,Janice W. Y. Wong,Janice W. Y. Wong,Lothar Rink,Florian D. Zepf +20 more
TL;DR: Depletion of CNS 5-HT via dietary TRP depletion appears to have no statistically significant short-term impact on cytokine concentrations in healthy adults, and future research on immunological stressors in combination with challenge techniques will be of value in order to further disentangle the complex interplay between brain 5- HT synthesis and immunological pathways.
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•Journal Article
Induction of cytokines in human peripheral blood and spleen cells by the Mycoplasma arthritidis-derived superantigen.
TL;DR: The results indicate that MAS induces different networks of cytokine interactions depending on the organ from which the cells are derived, and high titers of IL-4 and low IFN-gamma titers were observed in PBM and spleen cells.
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Influence of serum on zinc, toxic shock syndrome toxin-1, and lipopolysaccharide-induced production of IFN-gamma and IL-1 beta by human mononuclear cells.
TL;DR: It is found that the optimal stimulatory zinc concentration depended on the total protein content of the medium, whereas the monokine levels were dependent on the concentration of transport proteins such as transferrin.
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Induction of interleukin-6 in murine bone marrow-derived macrophages stimulated by the Mycoplasma arthritidis mitogen MAS.
TL;DR: It is demonstrated that MAS induces interleukin-6 (IL-6) in murine bone-marrow derived macrophage cultures using C3H/HeJ mice, which are known to be LPS-nonresponders, in all studies.
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