Lorraine Brennan

TL;DR: While previous studies of probiotics in healthy pregnant women showed some beneficial glycaemic effect, this randomised trial demonstrated no impact on fasting glucose or on obstetric outcomes in obese pregnancy.

TL;DR: The Waist-to-hip ratio and RA index were identified as significant modulators of beta-cell function and the ability of the RA index to modulate insulin secretion was confirmed in mechanistic studies.

TL;DR: A review of state of the art techniques employed when combining biomarker and self-reported data to account for measurement errors in dietary intake assessment shows that violation of the methods' assumptions negatively impacts resulting inference but that this impact is mitigated when the variation of the biomarker around the true intake is small.

TL;DR: Plasma LA is inversely associated with adiposity, followed by haplotypes of FADS1/2 genes, carbohydrate intakes, and dietary PUFA intakes; the association observed between plasma LA and adiposity may be linked to decreased de novo lipogenesis, insulin resistance, and inflammation.