Lore Zech
Karolinska Institutet
97 Papers
2.9K Citations
Lore Zech is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Chromosomal translocation & Quinacrine Mustard. The author has an hindex of 36, co-authored 97 publications. Previous affiliations of Lore Zech include University of Ljubljana & National Veterinary Institute.
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Papers
Characteristic chromosomal abnormalities in biopsies and lymphoid‐cell lines from patients with burkitt and non‐burkitt lymphomas
TL;DR: The karyotypes of cells from 10 Burkitt lymphoma biopsies, eight cell lines established from BL and nine cell lines from non‐BL sources were studied by chromosome banding techniques and it is suggested that the chromosome 14 marker represents a translocation between chromosomes 8 and 14,t (8q‐; 14q+).
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Chemical differentiation with fluorescent alkylating agents in Vicia faba metaphase chromosomes.
Torbjörn Caspersson,Torbjörn Caspersson,Lore Zech,Lore Zech,E.J. Modest,E.J. Modest,G.E. Foley,G.E. Foley,U. Wagh,U. Wagh,E. Simonsson,E. Simonsson +11 more
TL;DR: A bifunctional highly fluorescent quinacrine mustard was shown to give chromosome breaks preferentially localized to heterochromatic chromosome regions (identifiable by cold treatment) in the M-chromosome.
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DNA-binding fluorochromes for the study of the organization of the metaphase nucleus
Torbjörn Caspersson,Torbjörn Caspersson,Lore Zech,Lore Zech,E.J. Modest,E.J. Modest,G.E. Foley,G.E. Foley,U. Wagh,U. Wagh,E. Simonsson,E. Simonsson +11 more
TL;DR: Great and reproducible differences in the uptake of the fluorescent reagents by different chromosome regions were observed and a good correlation was found between regions reacting with several different fluorescent compounds and heterochromatin as defined by cold treatment.
277
Nonrandom chromosomal aberrations in chronic lymphocytic leukemia revealed by polyclonal B-cell-mitogen stimulation.
TL;DR: Peripheral blood lymphocytes from 11 patients with chronic lymphocytic leukemia were stimulated by Epstein-Barr virus, lipopolysaccharide from Escherichia, LPS, and phytohemagglutinin and revealed a normal karyotype, with the exception of a total of 4 metaphases in 3 patients.
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