Aging is the progressive loss of organ and tissue function over time. Growing older is positively linked to cognitive and biological degeneration such as physical frailty, psychological impairment, and cognitive decline. Oxidative stress is considered as an imbalance between pro- and antioxidant species, which results in molecular and cellular damage. Oxidative stress plays a crucial role in the development of age-related diseases. Emerging research evidence has suggested that antioxidant can control the autoxidation by interrupting the propagation of free radicals or by inhibiting the formation of free radicals and subsequently reduce oxidative stress, improve immune function, and increase healthy longevity. Indeed, oxidation damage is highly dependent on the inherited or acquired defects in enzymes involved in the redox-mediated signaling pathways. Therefore, the role of molecules with antioxidant activity that promote healthy aging and counteract oxidative stress is worth to discuss further. Of particular interest in this article, we highlighted the molecular mechanisms of antioxidants involved in the prevention of age-related diseases. Taken together, a better understanding of the role of antioxidants involved in redox modulation of inflammation would provide a useful approach for potential interventions, and subsequently promoting healthy longevity.

/pdf/antioxidant-and-oxidative-stress-a-mutual-interplay-in-age-22zo7ofsyc.pdf

Antioxidant and Oxidative Stress: A Mutual Interplay in Age-Related Diseases

The Basidiomycota constitutes a major phylum of the kingdom Fungi and is second in species numbers to the Ascomycota. The present work provides an overview of all validly published, currently used basidiomycete genera to date in a single document. An outline of all genera of Basidiomycota is provided, which includes 1928 currently used genera names, with 1263 synonyms, which are distributed in 241 families, 68 orders, 18 classes and four subphyla. We provide brief notes for each accepted genus including information on classification, number of accepted species, type species, life mode, habitat, distribution, and sequence information. Furthermore, three phylogenetic analyses with combined LSU, SSU, 5.8s, rpb1, rpb2, and ef1 datasets for the subphyla Agaricomycotina, Pucciniomycotina and Ustilaginomycotina are conducted, respectively. Divergence time estimates are provided to the family level with 632 species from 62 orders, 168 families and 605 genera. Our study indicates that the divergence times of the subphyla in Basidiomycota are 406–430 Mya, classes are 211–383 Mya, and orders are 99–323 Mya, which are largely consistent with previous studies. In this study, all phylogenetically supported families were dated, with the families of Agaricomycotina diverging from 27–178 Mya, Pucciniomycotina from 85–222 Mya, and Ustilaginomycotina from 79–177 Mya. Divergence times as additional criterion in ranking provide additional evidence to resolve taxonomic problems in the Basidiomycota taxonomic system, and also provide a better understanding of their phylogeny and evolution.

/pdf/notes-outline-and-divergence-times-of-basidiomycota-41rounhft0.pdf

Notes, outline and divergence times of Basidiomycota

Effect of high intensity ultrasound on structure and foaming properties of pea protein isolate.

Landmarks in the historical development of twenty first century food processing technologies

The huge land areas in China provide highly diverse habitats for macrofungi. Of these macrofungi, many are directly related to people’s daily life and have been utilized by ancient Chinese for at least 6800 years. In this study, we evaluate the current known resource diversity of Chinese macrofungi. A total of 1662 taxa are summarized, and all species names and their authorities have been checked and corrected according to authentic mycological databases. Among the 1662 taxa, 1020, 692, and 480 are considered to be edible, medicinal and poisonous mushrooms, respectively. A few of edible macrofungi in China are commonly used for commercial production. All known medicinal functions are labeled for medicinal species. The most common medicinal functions possessed by Chinese macrofungi are antitumor or anticancer, followed by antioxidant and antimicrobial. A total of 277 Chinese macrofungi are edible simultaneously with certain medicinal functions and without known toxicity. These species could be treated as “Gold Mushrooms”. Contrarily, 193 edible and/or medicinal species are also recognized as poisonous mushrooms. To avoid poisoning caused by these species, ingestion either in a proper way or in small amounts is important. However, the mycotoxins metabolized by these poisonous species could be a huge wealth of natural products yet to be explored. How to utilize these Chinese macrofungal resources is a critical to benefit humans worldwide.

Resource diversity of Chinese macrofungi: edible, medicinal and poisonous species.

Structural characterisation of polysaccharides from Tricholoma matsutake and their antioxidant and antitumour activities.

Defatted peanut meal hydrolysate (DPMH) was purified using ultrafiltration, gel filtration chromatography, and high-performance liquid chromatography. A tripeptide with strong oxygen radical absorbance capacity (ORAC) was isolated and identified as Tyr-Gly-Ser by ESI-MS/MS. It was then synthesized to measure its antioxidant properties in different systems. The ORAC value of Tyr-Gly-Ser was 3-fold higher than that of glutathione (GSH), and it displayed a stronger protective effect on linoleic acid peroxidation and H2O2-induced oxidative injury in rat pheochromocytoma line PC12 cells than GSH (p < 0.05). However, Tyr-Gly-Ser showed negligible DPPH radical scavenging activity, reducing power, and no metal chelating ability. The results suggested that Tyr-Gly-Ser displayed antioxidant activity via the hydrogen atom transfer mechanism, and the Tyr at the N-terminal was the hydrogen donor. The ORAC assay was recommended as a reliable and effective method to measure the antioxidant activity in the course of anti...

Isolation and characterization of an oxygen radical absorbance activity peptide from defatted peanut meal hydrolysate and its antioxidant properties.

Effects of limited enzymatic hydrolysis with pepsin and/or high-pressure homogenization in acid condition on the functional properties and structure characteristic of soybean protein isolate (SPI) were investigated. Functional properties, including protein solubility, surface hydrophobicity, particle size distribution, the ability of resisting freezing/thawing, foaming properties and dynamic surface properties were evaluated. Result showed that, single acid treatment could improve functional properties of SPI, but was not as effective as single or combined pepsin hydrolysis and high-pressure homogenization in acid condition. Emulsibility, the ability of resisting freezing/thawing and foaming capacity of soybean proteins were remarkably improved by the combination treatment, but no improvement of foaming stability was detected. Changes of structures were detected by surface hydrophobicity, and hydrodynamic diameter. It was found that aggregates existed in all treated samples. Besides, more flexible and soluble aggregates were observed in samples treated by limited pepsin proteolysis, high-pressure homogenization and the combination treatments, which might contribute to their functional properties.

Effects of limited enzymatic hydrolysis with pepsin and high-pressure homogenization on the functional properties of soybean protein isolate.

The invention discloses synthetic polypeptide and application thereof. The synthetic polypeptide has the following amino acid sequence: Tyr-Glu-Cys-Gly. The polypeptide is synthesized by using a polypeptide synthesizer by a solid-phase synthesis method. Through in-vitro antioxidant activity detectioon of the polypeptide, the polypeptide has high oxidation resistance; and when the synthetic polypeptide is applied to protection of nerve cells which are subjected to oxidative damage, cell survival rate is improved greatly, and an obvious effect is achieved.

Synthetic polypeptide and application thereof

Synthetic polypeptide and application of synthetic polypeptide

Handle everyday research tasks with reliable, citation-backed results

Your personal Research Agent to handle research tasks with citation-backed results

Popular Tasks used by Researchers

How can I help with your research?

Meet SciSpace

Get more enhanced response by uploading the PDFs you want me to reference.

No relevant PDFs in your library

SciSpace is the AI research assistant for academics. Run systematic literature reviews on 280M+ papers, and write papers with cited sources. Trusted by 1M+ students, PhDs & researchers.

SciSpace | AI for Research

Analyze PDFs

Code & Manuscripts

Funding & Grants

Literature & Patents

Medical & Clinical Data

Systematic Review

Visualize & Present

Web & Data

Build a Google Scholar-like website for your research.

Build a website

Create charts and images for your research

Create a Chart

Write a paper for submission to a journal

Draft a manuscript

Patent Search

Design eye-catching scientific posters in minutes.

Scientific Poster Generation

Systematic Literature Review

One task is running at the moment. Your messages will be shown right after.

Drag and drop or click here to browse

Loved by <highlight>1 million+</highlight> researchers

Extract a list of specific topics and their sources from unstructured text

Topics

Compare and analyze relevant papers that matches with your search

Papers

Get insights from PDFs and bookmarked papers from your library

My library

Recent searches

Try searching for:

Catch AI-generated content in scholarly and non-scholarly content

{ai} Detector

Ai Writer

Get PDF Summaries, highlighted text explanations 

Chat with PDF

Effortlessly create in-text citations and bibliographies in APA and 2,500 other formats

Citation generator

Get explanations, summaries, and answers on academic papers

Ease up your research workflow with {scispace}'s cohort of exciting AI tools

Elevate your academic writing skills and convey your ideas the way you want

Paraphraser

Explore our range of reading and writing tools

Your file is being prepared and should be ready in a few minutes. If it's a large file, it might take a bit longer. You can close this window, and we'll email you the file when it's done.

You have reached a maximum limit of <strong>{limit}</strong> columns in the table. Remove at least <strong>1</strong> column to add or create another one.

Longjian Gu

Author Tools

Chat about Author