Long Jiang
Capital Medical University
17 Papers
38 Citations
Long Jiang is an academic researcher from Capital Medical University. The author has contributed to research in topics: Familial hypercholesterolemia & Medicine. The author has an hindex of 8, co-authored 14 publications. Previous affiliations of Long Jiang include Cardiovascular Institute of the South.
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Papers
Characterization of the unique Chinese W483X mutation in the low-density lipoprotein–receptor gene in young patients with homozygous familial hypercholesterolemia
Long Jiang,Li-Yuan Sun,Xiao-Dong Pan,Pan-Pan Chen,Ling Tang,Wei Wang,Li-Min Zhao,Shi-Wei Yang,Lu-Ya Wang +8 more
TL;DR: The results suggest that younger HoFH patients with W483X mutations had a severe phenotype and should receive more aggressive treatment.
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The use of targeted exome sequencing in genetic diagnosis of young patients with severe hypercholesterolemia.
Long Jiang,Wen-Feng Wu,Li-Yuan Sun,Pan-Pan Chen,Pan-Pan Chen,Wei Wang,Wei Wang,Asier Benito-Vicente,Fan Zhang,Xiao-Dong Pan,Wei Cui,Shi-Wei Yang,Yu-Jie Zhou,César Martín,Lu-Ya Wang +14 more
TL;DR: TES is a very efficient tool for genetic diagnosis in young patients with severe hypercholesterolemia, and 7 patients were diagnosed with Heterozygous FH (HeFH) in which lipid levels were significantly higher than common HeFH patients.
Seven-year clinical follow-up of a Chinese homozygous familial hypercholesterolemia child with premature xanthomas and coronary artery disease--a need for early diagnosis and aggressive treatment.
Long Jiang,Feng Gao,Li-Bin Hu,Li-Yuan Sun,Xiao-Dong Pan,Jie Lin,Hai-bo Zhang,Qiang Yong,Qian Wang,Ya Yang,Chun-Mei Wang,Shi-Wei Yang,Feng Zhang,Feng Zhang,Lu-Ya Wang +14 more
TL;DR: This paper presents a poster presented at the China–Japan Friendship Hospital-China Academy of Sciences/National Engineering Laboratory for Druggable Gene and Protein Screening (CAS) for the first time in a public presentation about the design and application of nanofiltration membranes for the recovery ofatherosclerosis.
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Integrated analysis of microRNA and mRNA expression profiles in homozygous familial hypercholesterolemia patients and validation of atherosclerosis associated critical regulatory network.
Yue Wu,Yue Wu,Long Jiang,Huina Zhang,Shitong Cheng,Wenhui Wen,Liyuan Xu,Feng Zhang,Ya Yang,Lu-Ya Wang,Juan Chen +10 more
TL;DR: In this article, the authors performed high-throughput RNA and small RNA sequencing on the peripheral blood RNA samples of six HoFH patients and three healthy controls, and the gene and miRNA expression differences were analyzed, and seven miRNAs and six corresponding genes were screened out through regulatory network analysis.
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Low-density lipoprotein receptor genotypes modify the sera metabolome of patients with homozygous familial hypercholesterolemia
TL;DR: In this paper , the effects of LDLR genotype on holistic metabolome remain unclear and the authors present metabolomic, genetic, and clinical datasets from a large multi-center panel of 142 patients with LDLR-mutated HFH.
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