Liu Chen
12 Papers
Liu Chen is an academic researcher. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 2, co-authored 4 publications.
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Papers
The schemes, mechanisms and molecular pathway changes of Tumor Treating Fields (TTFields) alone or in combination with radiotherapy and chemotherapy
TL;DR: This review comprehensively summarizes the in-vitro effects, changes in pathways and molecules corresponding to relevant parameters of TTFields (frequency, intensity, and duration), and how to combine common tumor therapy such as radiotherapy and chemotherapy to obtain the maximum benefit.
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Heterogeneity of tumor immune microenvironment of EGFR/ALK-positive tumors versus EGFR/ALK-negative tumors in resected brain metastases from lung adenocarcinoma
Gang Xiao,Lifeng Li,Guilong Tanzhu,Zhiyuan Liu,Xuan Gao,Xingsheng Wan,Desheng Xiao,Liu Chen,Xuefeng Xia,Rongrong Zhou +9 more
TL;DR: In this paper , the authors found that lung adenocarcinomas (LUAD) with EGFR/ALK-positive BMs exhibited an immunosuppressive microenvironment, manifested as inhibition of immune-related pathways; low expression of immune checkpoint; decreased infiltration of CD8+T cells and cytotoxic lymphocyte; increased proportion of suppressive M2 macrophages.
A multiomics approach-based prediction of radiation pneumonia in lung cancer patients: impact on survival outcome
Lishui Niu,Xianjing Chu,Xianghui Yang,Hongxiang Zhao,Liu Chen,Fuxing Deng,Zhan Liang,Di Jing,Rongrong Zhou +8 more
TL;DR: Compared with the non-RP patients, the RP patients displayed longer OS, especially the mild RP patients, and the multiomics model contributed to improving the accuracy of RP prediction.
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The protein arginine methyltransferase family (PRMTs) regulates metastases in various tumors: From experimental study to clinical application.
Jiaoyang Ning,Liu Chen,Gang Xiao,Yu Zeng,Wen Shi,Guilong Tanzhu,Rongrong Zhou +6 more
- 09 Sep 2023
TL;DR: The development of inhibitors targeting arginine methylation, along with the progression of clinical trials, holds substantial potential in the field of tumor metastasis, meriting sustained attention.
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Radiotherapy in Preclinical Models of Brain Metastases: A Review and Recommendations for Future Studies
Wen Shi,Guilong Tanzhu,Liu Chen,Jiaoyang Ning,Hongji Wang,Gang Xiao,Haiqing Peng,Di Jing,Huadong Liang,Jing Nie,Min Yi,Rongrong Zhou +11 more
TL;DR: The theoretical underpinnings and practical applications of radiotherapy in combination with chemotherapy, targeted therapy, immunotherapy, and emerging technologies such as nanomaterials and oxygen-containing microbubbles are explored.
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