Lisa A. Snider

TL;DR: The recognition of the five criteria for PANDAS by Swedo et al established a homogenous subgroup of children with childhood onset obsessive–compulsive disorder (OCD) and/or tic disorders that is theorized to occur as a result of post-streptococcal autoimmunity in a manner similar to that of Sydenham's chorea.

TL;DR: Clinical and research findings in both immunology and neuropsychiatry have established the existence of post-streptococcal neuropsychiatric disorders and are beginning to shed light on possible pathobiologic processes.

TL;DR: Clinical improvements appeared to be more rapid and robust in the intravenous immunoglobulin and plasma exchange groups than in the prednisone group, and larger studies are required to confirm these clinical observations and to determine if these treatments are cost-effective for this disorder.

TL;DR: Motor/behavior changes were noted to occur in relationship to positive GAS culture with support that repeated GAS increases risk, and a strong seasonal pattern was found.