Lisa A. Ridnour
National Institutes of Health
125 Papers
481 Citations
Lisa A. Ridnour is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Nitric oxide & Cancer. The author has an hindex of 50, co-authored 107 publications. Previous affiliations of Lisa A. Ridnour include National Cancer Research Institute & Washington University in St. Louis.
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Papers
The chemical biology of nitric oxide: implications in cellular signaling.
Douglas D. Thomas,Lisa A. Ridnour,Jeff S. Isenberg,Wilmarie Flores-Santana,Christopher H. Switzer,Sonia Donzelli,Perwez Hussain,Cecilia Vecoli,Nazareno Paolocci,Stefan Ambs,Carol A. Colton,Curtis C. Harris,David D. Roberts,David A. Wink +13 more
TL;DR: Signal transduction and the chemical biology of NO in terms of the direct and indirect reactions are discussed, with general results that promote cell survival and proliferation, whereas higher levels favor cell cycle arrest, apoptosis, and senescence.
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Nitric oxide and redox mechanisms in the immune response
David A. Wink,Harry B. Hines,Robert Y.S. Cheng,Christopher H. Switzer,Wilmarie Flores-Santana,Michael P. Vitek,Lisa A. Ridnour,Carol A. Colton +7 more
TL;DR: The chemistry of NO and ROS in the context of antipathogen activity and immune regulation is discussed and similarities and differences between murine and human production of these intermediates are discussed.
738
Glucose deprivation-induced oxidative stress in human tumor cells. A fundamental defect in metabolism?
TL;DR: It is proposed that intracellular oxidation/reduction reactions involving hydroperoxides and thiols may provide a mechanistic link between metabolism, signal transduction, and gene expression in these human tumor cells.
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The chemistry of nitrosative stress induced by nitric oxide and reactive nitrogen oxide species. Putting perspective on stressful biological situations.
Lisa A. Ridnour,Douglas D. Thomas,Daniele Mancardi,Michael Graham Espey,Katrina M. Miranda,Nazareno Paolocci,Martin Feelisch,Jon M. Fukuto,David A. Wink +8 more
TL;DR: In this article, a review of the chemical aspects of nitrosative stress mediated by N2O3 is presented, and it is shown that the subtle balance between N 2O3 production and consumption may be involved in the etiology and control of various disease processes.
342
CD47 Is Necessary for Inhibition of Nitric Oxide-stimulated Vascular Cell Responses by Thrombospondin-1
Jeff S. Isenberg,Lisa A. Ridnour,Julie Dimitry,William A. Frazier,David A. Wink,David D. Roberts +5 more
TL;DR: Ligation of either CD36 or CD47 is sufficient to inhibit NO-stimulated vascular cell responses and cGMP signaling, but onlyCD47 is necessary for this activity of thrombospondin-1 at physiological concentrations.
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