Lionel Carneiro
University of Lausanne
26 Papers
9 Citations
Lionel Carneiro is an academic researcher from University of Lausanne. The author has contributed to research in topics: Energy homeostasis & Insulin. The author has an hindex of 14, co-authored 21 publications. Previous affiliations of Lionel Carneiro include Ohio State University & Paul Sabatier University.
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Papers
Mitochondrial reactive oxygen species are obligatory signals for glucose-induced insulin secretion.
Corinne Leloup,Cécile Tourrel-Cuzin,Christophe Magnan,Melis Karaca,Julien Castel,Lionel Carneiro,Anne-Laure Colombani,Alain Ktorza,Louis Casteilla,Luc Pénicaud +9 more
TL;DR: It is demonstrated that mROS production is a necessary stimulus for glucose-induced insulin secretion by investigating the mitochondrial origin of ROS (mROS) as the triggering signal.
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Resistance to Diet-Induced Obesity and Associated Metabolic Perturbations in Haploinsufficient Monocarboxylate Transporter 1 Mice
Sylvain Lengacher,Touria Nehiri-Sitayeb,Nadia Steiner,Lionel Carneiro,Céline Favrod,Frédéric Preitner,Bernard Thorens,Jean-Christophe Stehle,Laure Dix,François P. Pralong,Pierre J. Magistretti,Luc Pellerin +11 more
TL;DR: Interestingly, the enhancement in expression of several genes involved in lipid metabolism in the liver of MCT1 +/+ mice under high fat diet was prevented in the Liver of M CT1 +/− mice under the same diet, thus likely contributing to the observed phenotype.
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Tanycytes Regulate Lipid Homeostasis by Sensing Free Fatty Acids and Signaling to Key Hypothalamic Neuronal Populations via FGF21 Secretion.
Sarah Geller,Yoan Arribat,Citlalli Netzahualcoyotzi,Sylviane Lagarrigue,Lionel Carneiro,Lianjun Zhang,Francesca Amati,Isabel C. Lopez-Mejia,Luc Pellerin,Luc Pellerin +9 more
TL;DR: Tanycytes sense free fatty acids to maintain body lipid homeostasis through Fgf21 signaling within the hypothalamus, and deletion of tanycytic FgF21 triggers an increase in lipolysis.
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Glucose and hypothalamic astrocytes: More than a fueling role?
Corinne Leloup,Corinne Leloup,Corinne Leloup,Camille Allard,Camille Allard,Camille Allard,Lionel Carneiro,Lionel Carneiro,Lionel Carneiro,Xavier Fioramonti,Xavier Fioramonti,Xavier Fioramonti,Stephan Collins,Stephan Collins,Stephan Collins,Luc Pénicaud,Luc Pénicaud,Luc Pénicaud +17 more
TL;DR: Growing evidence suggest that astrocytes form a complex network and have to be considered as spatially coordinated and regulated metabolic units in physiological and pathological states.
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AMPK activation caused by reduced liver lactate metabolism protects against hepatic steatosis in MCT1 haploinsufficient mice.
Lionel Carneiro,Mohamed Asrih,Cendrine Repond,Christine Sempoux,Jean-Christophe Stehle,Corinne Leloup,François R Jornayvaz,Luc Pellerin,Luc Pellerin +8 more
TL;DR: It is proposed that reduced hepatic lactate metabolism is responsible for the protection against hepatic steatosis in MCT1 haploinsufficient mice via a constitutive activation of AMPK and repression of several major elements involved in hepatic lipid metabolism.
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