Linlin Xing
Tianjin University
5 Papers
Linlin Xing is an academic researcher from Tianjin University. The author has contributed to research in topics: Chemistry & Regioselectivity. The author has an hindex of 3, co-authored 5 publications.
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Papers
In Situ Formation of RSCl/ArSeCl and Their Application to the Synthesis of 4-Chalcogenylisocumarins/Pyrones from o-(1-Alkynyl)benzoates and ( Z)-2-Alken-4-ynoates.
TL;DR: The reaction of diorganyl disulfides or diselenides with PhICl2 in acetonitrile was found for the first time to lead to the in situ formation of organosulfenyl chloride or selenenyl salts resulting in the formation of 4-chalcogenylisocumarins/pyrones in good to excellent yields under metal-free conditions.
63
Synthesis of 4-Chloroisocoumarins via Intramolecular Halolactonization of o-Alkynylbenzoates: PhICl2-Mediated C-O/C-Cl Bond Formation.
TL;DR: A series of 4-chloroisocoumarins were conveniently synthesized from o-alkynylbenzoates via PhICl2-mediated intramolecular cyclization under metal-free conditions by virtue of mild reaction conditions, high-yielding products, simplified purification, and gram-scale synthesis.
28
Regioselective Chlorolactonization of Styrene-Type Carboxylic Esters and Amides via PhICl2-Mediated Oxidative C-O/C-Cl Bond Formations.
TL;DR: A metal-free regioselective intramolecular chlorolactonization process was proposed to involve a PhICl2-mediated oxidative C-O bond formation followed by C-Cl bond formation.
10
Patent
Synthetic method for NSC128981
Du Yunfei,Linlin Xing,Zhao Kang +2 more
- 29 Oct 2019
TL;DR: In this paper, a synthetic method for NSC128981 was described, which has the advantages of low price and easy availability of raw materials, high yield, high product purity, low cost and the like, and avoids the use of toxic or corrosive chlorination reagents.
Hypervalent Iodine-Mediated Synthesis of Spiroheterocycles via Oxidative Cyclization
Linlin Xing,Yong Zhang,Yunfei Du +2 more
TL;DR: This review article aims to briefly discuss strategies that have used hypervalent iodine reagents as oxidants to synthesize spiroheterocyclic compounds and to stimulate further study for novel syntheses of spiro heterocycleclic core structures using hypervalents iodine reagent under metal-free conditions.