Linjian Chen
9 Papers
Linjian Chen is an academic researcher. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 2, co-authored 5 publications.
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Papers
Lactate promotes endothelial-to-mesenchymal transition via Snail1 lactylation after myocardial infarction
Min Fan,Kun-peng Yang,Xiaohui Wang,Linjian Chen,P. Spencer Gill,Tuanzhu Ha,Li Lu,Nicole Lewis,David R. Williams,Chuanfu Li +9 more
TL;DR: In this article , a previously unknown function that increases cardiac fibrosis and exacerbates cardiac dysfunction by promoting EndoMT following myocardial infarction (MI) was reported.
148
CD163 protein inhibits lipopolysaccharide-induced macrophage transformation from M2 to M1 involved in disruption of the TWEAK–Fn14 interaction
Linjian Chen,Wanchun Mei,Juan Song,Kuncheng Chen,Wei Ni,Lin Wang,Zhaokai Li,Xiaofeng Ge,Liuhang Su,Binbin Liu,Cuilian Dai +10 more
TL;DR: Overall, the findings suggest that rmCD163 can inhibit the LPS-induced transformation of M2 macrophages to M1 by disrupting the TWEAK-Fn14 interaction and modulating the MAPK–NF–κB pathway.
3
San-wei-tan-xiang capsule attenuates atherosclerosis by increasing lysosomal activity in adipose tissue macrophages.
Heng Ye,Gang Wang,Xuchao Wang,Lin Wang,Weihua Ni,Linjian Chen,Yifan Zhu,Longshan Zhao,Zhili Xiong,Yan Wang,Cuilian Dai +10 more
TL;DR: In this article , the authors evaluated the chemical ingredients and mechanisms of SWTX capsule in anti-AS and found that SWTX could attenuate atherosclerotic plaque formation by elevating lysosomal activity and enhancing macrophage cholesterol efflux.
2
Association Between Serum Uric Acid Levels and Traditional Cardiovascular Risk Factors in Xiamen Residents of China: A Real-World Study
Feng Zhang,Linjian Chen,Zhaokai Li,Wei Ni,Lin Wang,Wanchun Mei,Guo-Mo Ruan,Zaixing Shi,Cuilian Dai +8 more
TL;DR: Serum uric acid was associated with several cardiovascular risk factors in Xiamen residents and the percentage of high 10-year ASDVD risk was higher in participants with hyperuricemia, which may experience cardiovascular benefit from uric Acid-lowering therapy.
The Efficacy and Safety of Phase I Cardiac Rehabilitation in Patients Hospitalized in Cardiac Intensive Care Unit With Acute Decompensated Heart Failure: A Study Protocol for a Randomized, Controlled, Clinical Trial
Linjing Wu,Jiahua Li,Linjian Chen,Mengmeng Xue,Yamin Zheng,Fan-Chen Meng,H. Jiang,Zaixing Shi,Peng Zhang,Cuilian Dai +9 more
TL;DR: Whether CR improves physical function and reduces rehospitalization in patients hospitalized in CICU withADHF is assessed to provide further research-based evidence for the clinical application of CR in patients with ADHF.