Lingxiang Ye
Johns Hopkins University
8 Papers
46 Citations
Lingxiang Ye is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Broccoli sprouts & Glucoraphanin. The author has an hindex of 6, co-authored 8 publications. Previous affiliations of Lingxiang Ye include Johns Hopkins University School of Medicine.
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Papers
Quantitative determination of dithiocarbamates in human plasma, serum, erythrocytes and urine: pharmacokinetics of broccoli sprout isothiocyanates in humans
Lingxiang Ye,Albena T. Dinkova-Kostova,Kristina L. Wade,Yuesheng Zhang,Theresa A. Shapiro,Paul Talalay +5 more
TL;DR: A sensitive and specific method for quantifying DTC levels in human plasma, serum, and erythrocytes has been devised.
396
Safety, tolerance, and metabolism of broccoli sprout glucosinolates and isothiocyanates: a clinical phase I study.
Theresa A. Shapiro,Jed W. Fahey,Albena T. Dinkova-Kostova,W. David Holtzclaw,Katherine K. Stephenson,Kristina L. Wade,Lingxiang Ye,Paul Talalay +7 more
TL;DR: A formal phase I study of safety, tolerance, and pharmacokinetics of broccoli sprouts appeared justified because these sprouts are being used as vehicles for the delivery of the glucosinolate glucoraphanin and its cognate isothiocyanate sulforaphane in clinical trials.
345
Protection against UV-light-induced skin carcinogenesis in SKH-1 high-risk mice by sulforaphane-containing broccoli sprout extracts
Albena T. Dinkova-Kostova,Stephanie N. Jenkins,Jed W. Fahey,Lingxiang Ye,Scott L. Wehage,Karen T. Liby,Katherine K. Stephenson,Kristina L. Wade,Paul Talalay +8 more
TL;DR: Topical application of sulforaphane-containing broccoli sprout extracts is a promising strategy for protecting against skin tumor formation after exposure to UV radiation.
232
Dietary glucoraphanin-rich broccoli sprout extracts protect against UV radiation-induced skin carcinogenesis in SKH-1 hairless mice
Albena T. Dinkova-Kostova,Albena T. Dinkova-Kostova,Jed W. Fahey,Andrea L. Benedict,Stephanie N. Jenkins,Lingxiang Ye,Scott L. Wehage,Paul Talalay +7 more
TL;DR: Feeding broccoli sprout extracts to SKH-1 hairless mice with prior chronic exposure to UV radiation inhibited the development of skin tumors during the subsequent 13 weeks, and tumor incidence, multiplicity, and volume were reduced in the animals that received the protective agent.
Erratum to “Quantitative determination of dithiocarbamates in human plasma, serum, erythrocytes and urine: pharmacokinetics of broccoli sprout isothiocyanates in humans” [Clin. Chim. Acta 316 (2002) 43–53]
Lingxiang Ye,Albena T. Dinkova-Kostova,Kristina L. Wade,Yuesheng Zhang,Theresa A. Shapiro,Paul Talalay +5 more
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