Lingmin Lin
9 Papers
2 Citations
Lingmin Lin is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 1, co-authored 7 publications.
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Papers
Porous microneedle patch with sustained delivery of extracellular vesicles mitigates severe spinal cord injury
Ao Fang,Nai-Yang Guan,Yanming Zuo,Lingmin Lin,Binjie Guo,Yile Wu,Xurong Lin,Wanxiong Cai,Xiangfeng Chen,Jingjia Ye,Zeinab Abdelrahman,Xiaodan Li,Hanyu Zheng,Zhonghan Wu,Shuang Jin,Kan Xu,Yan Huang,Xiaosong Gu,Bin Yu,Xuhua Wang +19 more
TL;DR: In this article , a mesenchymal stem cells and porous microneedles are used to deliver extracellular vesicles for spinal cord injury treatment, which reduces the cavity and scar tissue formation, promotes angiogenesis, and improves survival of nearby tissues and axons.
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Controlled delivery of a neurotransmitter-agonist conjugate for functional recovery after severe spinal cord injury.
Yanming Zuo,Jingjia Ye,Wanxiong Cai,Binjie Guo,Xiangfeng Chen,Lingmin Lin,Shuang Jin,Hanyu Zheng,Ao Fang,Xingran Qian,Zeinab Abdelrahman,Zhiping Wang,Zhipeng Zhang,Zuobing Chen,Bin Yu,Xiaosong Gu,Xuhua Wang +16 more
TL;DR: The delivery of neurotransmitter-conjugated KCC2 agonist is delivered using a reactive oxygen species–responsive polymer nanoparticle that can cross the damaged blood–spinal cord barrier and significantly increase recovery after spinal cord injury in vivo.
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ROS filter coating scaffold protects 3D mesenchymal stem cell spheroids for dual-phase treatment of spinal cord injury
Jian-feng Cao,Jiahe Wu,Jiafu Mu,Lingmin Lin,Xunqi Zhang,Tianchen Huang,Teng Ma,Manning Zhu,Xiaoyang Dai,Xuhua Wang,Shiqing Feng,Jian-Qing Gao +11 more
TL;DR: In this paper , a composite scaffold system (RF-pGel-MS), which consisted of an outer ROS filter and an inner porous GelMA hydrogel harbored with mesenchymal stem cells (MSs), was designed for SCI repair.
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An engineering-reinforced extracellular vesicle–integrated hydrogel with an ROS-responsive release pattern mitigates spinal cord injury
Jian Cao,Xunqi Zhang,Jing Guo,Jiahe Wu,Lingmin Lin,Xurong Lin,Jiafu Mu,Tianchen Huang,Manning Zhu,Lan Ma,Weihang Zhou,Xuhua Wang,Shiqing Feng,Jianqing Gao +13 more
7
Porous microneedle patch with sustained exosomes delivery repairs severe spinal cord injury
Ao Fang,Yifan Wang,Nai-Yang Guan,Lingmin Lin,Binjie Guo,Wanxiong Cai,Xiangfeng Chen,Jingjia Ye,Zeinab Abdelrahman,Shuang Jin,Xiaosong Gu,Bin Yu,Xuhua Wang +12 more
TL;DR: The MN-MSC patch device proposed here breaks through the current dilemma from the contradiction between treatment efficacy and ethical issues in treating acute SCI and leads to reduced cavity and scar tissue formation, angiogenesis, and the survival of spared tissues/axons.