Ling Jiang
Zhejiang University
9 Papers
49 Citations
Ling Jiang is an academic researcher from Zhejiang University. The author has contributed to research in topics: Esterase & Catalysis. The author has an hindex of 6, co-authored 9 publications. Previous affiliations of Ling Jiang include Zhejiang University of Technology.
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Papers
Enhanced enantioselectivity of a carboxyl esterase from Rhodobacter sphaeroides by directed evolution
TL;DR: Conformation analysis revealed that the enhanced enantioselectivity of variant CH for the seven substrates applied in this study was derived from the decrease in size of the substrate binding pocket.
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A tandem and fully enzymatic procedure for the green resolution of chiral alcohols: acylation and deacylation in non-aqueous media
TL;DR: A green and fully enzymatic procedure for the resolution of chiral alcohols through lipase/esterase-catalyzed acylation and subsequent lipase-Catalyzed aminolysis using anhydrous ammonia was demonstrated.
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Catalytic promiscuity of Escherichia coli BioH esterase: Application in the synthesis of 3,4-dihydropyran derivatives
TL;DR: In this paper, 10 enzymes were investigated for the promiscuous activity in catalysis of the Michael addition-cyclization cascade reaction of p-nitrobenzalacetone with 1,3-cyclohexanedione to prepare 2-hydroxy-2-methyl-4-(4-nitrophenyl)-3,4,7,8-tetrahydro-2H-chromen-5(6H)-one.
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Enzymatic Promiscuity： Escherichia coli BioH Esterase-catalysed Aldol Reaction and Knoevenagel Reaction
Ling Jiang,Hongwei Yu +1 more
TL;DR: Esterase BioH, which is obligatory for biotin synthesis in Escherichia coli, was found to exhibit a promiscuous ability to catalyse Aldol and Knoevenagel reactions with moderate to good yields, which expand the field of enzymatic promiscuity.
13
Mechanochemical enzymatic synthesis of 1,4‐dihydropyridine calcium antagonists and derivatives
TL;DR: In this paper, a solvent free quick synthesis of 1,4-Dihydropyridine (1,4−DHP) calcium antagonists was achieved by Lipozyme® RM IM (triacylglycerol acylhydrolase, EC3.1.3) under ball-milling conditions.
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