Linda Partridge
Max Planck Society
518 Papers
5.7K Citations
Linda Partridge is an academic researcher from Max Planck Society. The author has contributed to research in topics: Biology & Population. The author has an hindex of 118, co-authored 491 publications. Previous affiliations of Linda Partridge include University of York & University College London.
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Papers
Optimality, mutation and the evolution of ageing
TL;DR: Evidence for the importance of both selection against late-acting mutations and selection against deleterious mutations is emerging, and unravelling their relative importance presents experimentalists with a major challenge.
Comment on brain IRS2 signaling coordinates life span and nutrient homeostasis
TL;DR: No evidence is found for life-span extension in mice heterozygous for a null mutation in insulin receptor substrate–2 (Irs2), and it is suggested that the findings of Taguchi et al. were due to atypical life- spans in their study animals.
Evolution and development of body size and cell size in drosophila melanogaster in response to temperature.
TL;DR: The increase in body size and cell size resulting from development at low temperature may be a case of adaptive phenotypic plasticity, and the pattern of plasticity did not evolve in response to temperature for any of the traits.
Deletion of endogenous Tau proteins is not detrimental in Drosophila
Sylvie Burnouf,Sebastian Grönke,Hrvoje Augustin,Jacqueline Dols,Marianna Karina Gorsky,Jennifer A Werner,Fiona Kerr,Nazif Alic,Pedro Martinez,Linda Partridge +9 more
TL;DR: It is observed that the specific removal of endogenous dTau proteins did not lead to overt, macroscopic phenotypes in flies, and suggests that the tau KO strain is a relevant model to further investigate the role of dT Tau proteins in vivo, thereby giving additional insights into hTau functions.
The genetic bases of divergence in desiccation and starvation resistance among tropical and temperate populations of Drosophila melanogaster.
TL;DR: The presence of epistatic effects in approximately half of the models presented in this study is consistent with line-cross studies of diverged traits in other animals, and does not support the view that epistasis is the predominant means by which populations diverge.