Linda Partridge
Max Planck Society
518 Papers
5.7K Citations
Linda Partridge is an academic researcher from Max Planck Society. The author has contributed to research in topics: Biology & Population. The author has an hindex of 118, co-authored 491 publications. Previous affiliations of Linda Partridge include University of York & University College London.
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Papers
Intervening in ageing to prevent the diseases of ageing
TL;DR: This article showed that ageing in diverse animals, including humans, is malleable to specific types of genetic mutation, diet, and drugs that can extend lifespan and improve health during ageing, pointing to the prospect of broad-spectrum preventive medicine for the diseases of ageing based on intervention in relevant aspects of the ageing process itself.
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Natural Selection: Evolving evolvability
TL;DR: In yeast, a modified protein known as a prion generates variation in growth rate across diverse environments, which is an example of an agent that has evolved in order to promote its possessor's adaptability.
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Evolutionary responses of Drosophila melanogaster life history to differences in larval density
TL;DR: The results suggest that larval density does have important effects on the expression and resolution of life history trade‐offs in Drosophila melanogaster, but that these may be somewhat different from those reported in previous studies.
60
Complementation between polymerase- and exonuclease-deficient mitochondrial DNA polymerase mutants in genomically engineered flies
Ana Bratic,Timo E.S. Kauppila,Bertil Macao,Sebastian Grönke,Triinu Siibak,James B. Stewart,Francesca Baggio,Jacqueline Dols,Linda Partridge,Maria Falkenberg,Anna Wredenberg,Nils-Göran Larsson +11 more
TL;DR: Genomically engineer the tamas locus, encoding fly POLγA, and introduce alleles expressing exonuclease- (exo−) and polymerase-deficient (pol−) polγA versions to increase the fidelity of the catalytic subunit (POLγA) of the mtDNA polymerase.
Functional conservation in genes and pathways linking ageing and immunity.
Daniel K. Fabian,Matías Fuentealba,Matías Fuentealba,Handan Melike Dönertaş,Linda Partridge,Linda Partridge,Janet M. Thornton +6 more
TL;DR: The authors provided a compilation of genes concomitantly known to be involved in immunity and ageing in humans and three well-studied model organisms, the nematode worm Caenorhabditis elegans, the fruit fly Drosophila melanogaster, and the house mouse Mus musculus.