Lin Yang
Chinese Academy of Sciences
16 Papers
27 Citations
Lin Yang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Hermansky–Pudlak syndrome & Neuropathy target esterase. The author has an hindex of 9, co-authored 16 publications.
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Papers
Joint toxicity of chlorpyrifos and cadmium on the oxidative stress and mitochondrial damage in neuronal cells
TL;DR: Results showed that CPF and Cd generated protein and lipid peroxidation, disturbed the total antioxidant capability, and altered mitochondria ultrastructure in the brain of rats exposed subchronically to organophosphorus pesticide chlorpyrifos and heavy metal cadmium, and their mixtures at the environmentally relevant doses.
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An NMR-based metabonomic investigation of the subacute effects of melamine in rats.
TL;DR: The results indicate that melamine not only caused renal disfunction but also disturbed the liver's glucose, protein, and nitrogen metabolism.
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NGS-based 100-gene panel of hypopigmentation identifies mutations in Chinese Hermansky-Pudlak syndrome patients.
Aihua Wei,Yefeng Yuan,Dayong Bai,Jing Ma,Zhenhua Hao,Yingzi Zhang,Jiaying Yu,Zhiyong Zhou,Lin Yang,Xiumin Yang,Li Li,Wei Li +11 more
TL;DR: Using next‐generation sequencing (NGS), the feasibility and utility of NGS‐based panel diagnostics for HPS are demonstrated andGenotyping of HPS subtypes is a prerequisite for intervention of subtype‐specific symptoms.
35
Changes in metabolic profiles of urine from rats following chronic exposure to anticholinesterase pesticides
Hui-Ping Wang,Yu-Jie Liang,Qi Zhang,Ding-Xin Long,Wei Li,Li Li,Lin Yang,Xian-Zhong Yan,Yi-Jun Wu +8 more
TL;DR: The results suggest that chronic exposure to chlorpyrifos and carbaryl alone, or in combination could cause disturbance of metabolic function in liver mitochondria and renal failure.
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G protein β2 subunit interacts directly with neuropathy target esterase and regulates its activity
TL;DR: Findings suggest that Gbeta2 may play a significant role in maintaining the activity of NTE, a novel phospholipase B anchored to the cytoplasmic face of endoplasmic reticulum and essential for embryonic and nervous development.
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