Lin Sun
University of Macau
12 Papers
16 Citations
Lin Sun is an academic researcher from University of Macau. The author has contributed to research in topics: Chemistry & Transdermal patch. The author has an hindex of 9, co-authored 12 publications. Previous affiliations of Lin Sun include Shenyang Pharmaceutical University & Zunyi Medical College.
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Papers
Enhanced topical penetration, system exposure and anti-psoriasis activity of two particle-sized, curcumin-loaded PLGA nanoparticles in hydrogel
Lin Sun,Zeyu Liu,Lun Wang,Dongmei Cun,Henry H.Y. Tong,Ru Yan,Xin Chen,Ruibing Wang,Ying Zheng +8 more
TL;DR: E encapsulation of Cur into PLGA NPs, particularly for NPs of 50 nm, could facilitate lipophilic Cur's dispersion, sustained‐release, accumulation, and penetration across the skin and into the blood circulation, which significantly improves anti‐psoriasis activity in mice.
185
Loading of water-insoluble celastrol into niosome hydrogels for improved topical permeation and anti-psoriasis activity.
TL;DR: In conclusion, encapsulation of celastrol by niosomes increased the water-solubility and permeation of Celastrol into the skin, significantly improving its anti-psoriasis activity in mice.
96
The relationship between hydrogen-bonded ion-pair stability and transdermal penetration of lornoxicam with organic amines
TL;DR: The results demonstrated that the stability of ion-pair complexes was closely related with the basicity of organic amines and exhibited a great contribution on skin permeation of LOX.
26
Effects of nanosuspension formulations on transport, pharmacokinetics, in vivo targeting and efficacy for poorly water-soluble drugs.
TL;DR: This review will correlate characteristics of nanosuspension formulations, including drug property, particle size, crystallinity, stabiliser and surface property, with their transport, pharmacokinetics, bioactivity and toxicity after delivery by different administration routes.
12
Blends of hydrophobic and swelling agents in the swelling layer in the preparation of delayed-release pellets of a hydrophilic drug with low MW: Physicochemical characterizations and in-vivo evaluations
TL;DR: Bl blends of hydrophobic and swelling agents in the swelling layer in double-membrane pellets could achieve a delayed drug-release profile in Vitro, as well as delayed and sustained absorption in vivo for highly soluble, low-MW drug.
10