Lin Hou
Qingdao University
40 Papers
78 Citations
Lin Hou is an academic researcher from Qingdao University. The author has contributed to research in topics: Apoptosis & Biology. The author has an hindex of 11, co-authored 35 publications.
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Papers
Anticancer properties and mechanisms of fucoidan on mouse breast cancer in vitro and in vivo.
TL;DR: The findings indicated that crude fucoidan inhibited mouse breast cancer growth in vitro and in vivo, and suggest thatfucoidan may serve as a potential therapeutic agent for breast cancer.
Docosahexaenoic acid inhibited the Wnt/β-catenin pathway and suppressed breast cancer cells in vitro and in vivo.
TL;DR: It is found that feeding mouse the 5% fish oil-supplemented diet for 30 days significantly reduced the growth of 4T1 mouse breast cancer in vivo through inhibition of cancer cell proliferation as well as induction of apoptosis.
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Fucoidan inhibited 4T1 mouse breast cancer cell growth in vivo and in vitro via downregulation of Wnt/β-catenin signaling.
TL;DR: It is suggested that fucoidan exerts its anticancer activity through downregulation of Wnt/β-catenin signaling, and may be an effective therapy for the chemoprevention and treatment of mouse breast cancer.
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Pro-inflammatory cytokine-mediated ferroportin down-regulation contributes to the nigral iron accumulation in lipopolysaccharide-induced Parkinsonian models
TL;DR: Results suggested that pro-inflammatory cytokines might induce Fpn downregulation, which leads to iron accumulation and dopaminergic neurons' degeneration in PD.
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Fucoidan prevent murine autoimmune diabetes via suppression TLR4-signaling pathways, regulation DC/Treg induced immune tolerance and improving gut microecology
TL;DR: Fucoidan could prevent the development of autoimmune diabetes in NOD mice via regulating DC/Treg induced immune tolerance, improving gut microecology, down-regulating TLR4 signaling pathway, and maintaining pancreatic internal environment.