6 Papers
Lin He is an academic researcher from East China Normal University. The author has contributed to research in topics: Sterility & Bombyx mori. The author has an hindex of 4, co-authored 6 publications.
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Papers
Mutation of the seminal protease gene, serine protease 2, results in male sterility in diverse lepidopterans.
Xia Xu,Yaohui Wang,Hong-Lun Bi,Jun Xu,Zulian Liu,Chang-Ying Niu,Lin He,Anthony A. James,Kai Li,Yongping Huang +9 more
TL;DR: The conclusion that Ser2 gene is necessary for male reproductive success in diverse lepidopterans is supported, as CRISPR/Cas9 technology disrupting Ser2 resulted in dominant heritable male sterility and no differences in other reproductive behaviors in the mutant males are detected.
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CRISPR/Cas9-mediated ebony knockout results in puparium melanism in Spodoptera litura
TL;DR: This study clearly demonstrates the function of ebony in the puparium coloration and also provides a potentially useful marker gene for functional studies in S. litura as well as other lepidopteran pests.
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Disruption of the ovarian serine protease (Osp) gene causes female sterility in Bombyx mori and Spodoptera litura
Xia Xu,Xia Xu,Hong-Lun Bi,Hong-Lun Bi,Yaohui Wang,Xiaowei Li,Jun Xu,Zulian Liu,Lin He,Kai Li,Yongping Huang +10 more
TL;DR: It is found that the deletion of Osp resulted in female sterility, whereas male fertility was not affected and this gene is a potential molecular target for genetic-based pest management.
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Disruption of egg-specific protein causes female sterility in Bombyx mori.
TL;DR: In this paper, the authors explored the gene function of Esp through transgenic clustered regularly interspaced palindromic repeats (CRISPR) / CRISPR-associated protein 9 technology-mediated mutations in the silkworm.
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BmHpo mutation induces smaller body size and late stage larval lethality in the silkworm, Bombyx mori.
TL;DR: The data show that BmHpo is essential for regulation of insect growth and development and that CRISPR/Cas9 technology can serve as a basis for functional analysis of target genes in lepidopteran insects.
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