5 Papers
Lin Ge is an academic researcher from State University of New York Upstate Medical University. The author has contributed to research in topics: ARDS & Lung injury. The author has an hindex of 5, co-authored 5 publications.
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Papers
Early airway pressure release ventilation prevents ARDS-a novel preventive approach to lung injury.
Shreyas Roy,Nader M. Habashi,Benjamin Sadowitz,Penny Andrews,Lin Ge,Guirong Wang,Preyas Roy,Auyon J. Ghosh,Michael Kuhn,Joshua Satalin,Louis A. Gatto,Xin Lin,David A. Dean,Yoram Vodovotz,Gary F. Nieman +14 more
TL;DR: It is hypothesized that early application of a protective ventilation strategy (airway pressure release ventilation [APRV] will stabilize alveoli and reduce alveolar edema, preventing the development of acute respiratory distress syndrome (ARDS).
Early stabilizing alveolar ventilation prevents acute respiratory distress syndrome: a novel timing-based ventilatory intervention to avert lung injury.
Shreyas Roy,Benjamin Sadowitz,Penny Andrews,Louis A. Gatto,William Marx,Lin Ge,Guirong Wang,Xin Lin,David A. Dean,Michael Kuhn,Auyon J. Ghosh,Joshua Satalin,Kathy Snyder,Yoram Vodovotz,Gary F. Nieman,Nader M. Habashi +15 more
TL;DR: Early preventative mechanical ventilation with APRV blocked ARDS development, preserved surfactant proteins, and reduced pulmonary inflammation and edema despite systemic inflammation similar to NPV.
Airway Pressure Release Ventilation Prevents Ventilator-Induced Lung Injury in Normal Lungs
Bryanna Emr,Louis A. Gatto,Shreyas Roy,Joshua Satalin,Auyon J. Ghosh,Kathy Snyder,Penny Andrews,N.M. Habashi,William Marx,William Marx,Lin Ge,Guirong Wang,David A. Dean,Yoram Vodovotz,Gary F. Nieman +14 more
TL;DR: The data suggest that APRV applied early could reduce the incidence of ARDS in patients at risk, and mechanical ventilation with tidal volume and positive end-expiratory pressure settings used routinely on surgery patients caused ALI.
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Preemptive application of airway pressure release ventilation prevents development of acute respiratory distress syndrome in a rat traumatic hemorrhagic shock model.
Shreyas Roy,Bryanna Emr,Benjamin Sadowitz,Louis A. Gatto,Auyon J. Ghosh,Joshua Satalin,Kathy Snyder,Lin Ge,Guirong Wang,William Marx,David A. Dean,Penny Andrews,Anil Singh,Thomas M. Scalea,Nader M. Habashi,Gary F. Nieman +15 more
TL;DR: The findings demonstrate that preemptive mechanical ventilation with APRV attenuates the clinical and histologic lung injury associated with T/HS, and the mechanism of injury prevention is related to preservation of alveolar epithelial and endothelial integrity.
Differential susceptibility of human sp-b genetic variants on lung injury caused by bacterial pneumonia and the effect of a chemically modified curcumin.
Yongan Xu,Lin Ge,Osama A. Abdel-Razek,Sumeet Jain,Zhiyong Liu,Yucai Hong,Gary F. Nieman,Francis Johnson,Lorne M. Golub,Robert N. Cooney,Guirong Wang +10 more
TL;DR: It is concluded that mice withSP-B-C allele are more susceptible to S. aureus pneumonia than mice with SP- B-T allele, and that CMC2.24 attenuates lung injury thus reducing mortality.